Evidence map›Paper›PMID 31702626›Full record

ArticleMedicine2019

Transcutaneous posterior tibial nerve stimulation in children and adolescents with functional constipation: A protocol for an interventional study.

Rebeca Mayara Padilha Rego, Nilton Carlos Machado, Mary de Assis Carvalho, Johann Souza Graffunder, Erika Veruska Paiva Ortolan, Pedro Luiz Toledo de Arruda Lourenção

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  8. Pediatric gastrointestinal neuromodulation: A review.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rebeca Mayara Padilha RegoUNESP - São Paulo State University, Botucatu Medical School, Botucatu.
Nilton Carlos MachadoUNESP - São Paulo State University, Botucatu Medical School, Department of Pediatrics, Pediatric Gastroenterology, Hepatology and Nutrition Division, Botucatu.
Mary de Assis CarvalhoUNESP - São Paulo State University, Botucatu Medical School, Department of Pediatrics, Pediatric Gastroenterology, Hepatology and Nutrition Division, Botucatu.
Johann Souza GraffunderUNESP - São Paulo State University, Botucatu Medical School, Botucatu.
Erika Veruska Paiva OrtolanUNESP - São Paulo State University, Botucatu Medical School, Department of Surgery and Orthopedics, Pediatric Surgery Division, Botucatu, SP, Brazil.
Pedro Luiz Toledo de Arruda LourençãoUNESP - São Paulo State University, Botucatu Medical School, Department of Surgery and Orthopedics, Pediatric Surgery Division, Botucatu, SP, Brazil.
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA vast majority of children with functional constipation respond to the standard medical treatment. However, a subset of patients may present with an unsatisfactory response and only minor improvement of symptoms. Transcutaneous posterior tibial nerve stimulation (PTNS) involves electrical stimulation of the posterior tibial nerve at the level of the ankle, transcutaneously through electrodes fixated on the overlying skin. Stimulation of the tibial nerve can modulate urinary and defecatory function through the stimulation of sacral nerves. Thus, transcutaneous PTNS can be considered a very promising, noninvasive, and safe method to be used in the pediatric age group. However, there is still no published study that has investigated its use in children for the treatment of intestinal constipation. This is a single-center, prospective, longitudinal, and interventional study designed to assess the applicability and clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation. Children will be submitted to daily sessions of transcutaneous PTNS for a period of 4 weeks. All children will also be invited to participate in semistructured interviews, 1 in each of the 3 assessments: 1 week before the start of the intervention; immediately after the 4 weeks of intervention; and 4 weeks after the end of the intervention period. In these interviews, the aspects related to bowel habits and quality of life will be assessed. This project aims to evaluate the clinical outcomes of transcutaneous PTNS in children with functional intestinal constipation and the applicability of this kind of treatment.

conclusionsThis protocol intended to demonstrate the efficacy of this promising method to increase the number of bowel movements and the stool consistency, to reduce the number of episodes of retentive fecal incontinence, and to indirectly improve the overall quality of life.

Indexed as

AdolescentChildClinical Trials as TopicConstipationFecal IncontinenceHumansLongitudinal StudiesMaleProspective StudiesQuality of LifeTibial NerveTranscutaneous Electric Nerve StimulationTreatment Outcome

Identifiers

PMID31702626
PMCPMC6855522
OpenAlexW2984998956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.