Evidence map›Paper›PMID 31702550›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2020

Effect of centralization on complex surgical care: A population-based case study of radical cystectomy.

D Robert Siemens, Kash Visram, Xuejiao Wei, Christopher Booth

Abstract read
In one paragraph

Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Inappropriate use of clinical practices in Canada: a systematic review.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Pooled it
  2. The Financial Argument for Centralization of Care for Esophagectomy.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
    Article
  3. Complete response: A lens into the future of urology?Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  4. Impact of travel distance on short-term outcomes in patients receiving treatment for urolithiasis A population-based study.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  5. The anesthesia human resources crisis in Canada.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Article
  6. Real-life benchmarking bladder cancer care: A population-based study.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023
    Article
  7. Article
  8. Article
  9. Improving outcomes of radical cystectomy: A call for passive over active regionalization.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

D Robert SiemensDepartment of Urology, Queen's University, Kingston, ON, Canada.
Kash VisramDepartment of Urology, Queen's University, Kingston, ON, Canada.
Xuejiao WeiDepartment of Public Health Sciences, Queen's University, Kingston, ON, Canada.
Christopher BoothDepartment of Oncology, Queen's University, Kingston, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe sought to determine whether non-mandated or passive centralization of radical cystectomy (RC) to higher-volume centers leads to enhanced processes of care and outcomes.

methodsThis is a population-based, retrospective, cohort study that used the Ontario Cancer Registry (OCR) to identify all incident patients who underwent RC from 1994-2013. Electronic records of treatment were linked to OCR; pathology records were obtained for all cases and reviewed by a team of trained data abstractors. The primary objective was to describe annual provider RC volumes. Secondary objectives included investigating process and outcome measures.

resultsFor the 5574 patients identified, the mean annual surgeon volume and hospital volume of RC from 1994-2008 was 4.5 (95% confidence interval [CI] 4.4-4.7) and 12.2 (95% CI 11.8-12.5), respectively. From 2009-2013, these volumes significantly increased to 6.8 (95% CI 6.5-7. 1) and 16.4 (95% CI 15.8-16.9). Process variables improved over time, including the use of neoadjuvant chemotherapy. Over the study period, there was a substantial improvement in cancer-specific survival (CSS): hazard ratio (HR) 0.60 (95% CI 0.53-0.67) for 2009-2013. During the most recent era, there was still evidence of a provider volume effect on both process measures and CSS.

conclusionsThere has been recent passive centralization of RC to higher-volume providers in the province of Ontario, with measurable improvements in processes of quality care. Although centralization was also associated with improvement in CSS, in the most recent era, there continues to be low-volume providers with a residual volume-outcome effect.

Identifiers

PMID31702550
PMCPMC7124168

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.