Evidence map›Paper›PMID 31702480›Full record

ArticleHuman vaccines & immunotherapeutics2020

Emerging CAR T cell therapies: clinical landscape and patent technological routes.

Virgínia Picanco-Castro, Cristiano Gonçalves Pereira, Kamilla Swiech, Kelen Cristina Ribeiro Malmegrim, Dimas Tadeu Covas, Geciane Silveira Porto

Open access · greenAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Car T Cells in Solid Tumors: Overcoming Obstacles.International journal of molecular sciences · 2024
    Review
  4. Review
  5. Article
  6. Adoptive T-cell Immunotherapy: Perfecting Self-Defenses.Experientia supplementum (2012) · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Virgínia Picanco-CastroCenter for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.ORCID 0000-0001-8474-4610
Cristiano Gonçalves PereiraSchool of Economics, Business Administration and Accounting, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.ORCID 0000-0003-0364-7793
Kamilla SwiechCenter for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.ORCID 0000-0002-4811-9751
Kelen Cristina Ribeiro MalmegrimCenter for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.ORCID 0000-0002-9303-0086
Dimas Tadeu CovasCenter for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.ORCID 0000-0002-7364-2595
Geciane Silveira PortoSchool of Economics, Business Administration and Accounting, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.ORCID 0000-0001-6104-3627
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study is to mine CAR-T patents and therapies under development, to design a landscape of the sector and to understand key therapy segments and their current trends. The study analyzed the entire market, consisting of 1624 patent families and 509 biologics under development, to depict an overview of the CAR-T therapies and their state of the art. Our results showed cutting-edge inventions, the major players, the dynamics of cooperation among institutions, the progress of the therapies' generation over the years and future innovation pathways. CAR-T therapies are transforming the current scenario for cancer treatment, and this study reveals the picture of what we can likely expect ahead in order to assist scientists at the academy and industry to improve their research strategies.

Indexed as

Immunotherapy, AdoptiveInventionsCAR-T cellsclinical trialsPatent landscapetechnology forecasting

Identifiers

PMID31702480
PMCPMC7482707
OpenAlexW2985492523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.