Evidence map›Paper›PMID 31701397›Full record

ArticleTropical animal health and production2020

Implications for dosing regimen of enrofloxacin administered concurrently with dexamethasone in febrile buffalo calves.

Pritam K Sidhu, Balaje Ramalingam, Gurpreet Kaur, Satyavan Rampal, Johann F Coetzee

Abstract read
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In one paragraph

Article in Tropical animal health and production, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Pritam K SidhuDepartment of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA. pritams@ksu.edu.ORCID http://orcid.org/0000-0003-3784-5982
Balaje RamalingamGuru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.
Gurpreet KaurGuru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.
Satyavan RampalGuru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.
Johann F CoetzeeDepartment of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, 66506, USA.
Guru Angad Dev Veterinary and Animal Sciences University · INKansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the study was to determine the influence of dexamethasone (DXM) on pharmacokinetics (PK) and pharmacodynamics (PD) of enrofloxacin (ENR) for dosage optimization following concurrent administration of ENR and DXM in febrile buffalo calves. A 2 μg/kg intravenous dosage of lipopolysaccharide derived from Escherichia coli was used to induce fever in calves. After inducing fever, ENR was administered at the dose rate of 12 mg/kg, IM followed by IM injection of DXM (0.05 mg/kg) in calves. Minor alterations in PK of ENR were observed following the administration of ENR + DXM. The PK parameters were t

Indexed as

BuffaloesAnimalsAnti-Bacterial AgentsDexamethasoneDose-Response Relationship, DrugDrug Therapy, CombinationEnrofloxacinEscherichia coliFeverInjections, IntramuscularLipopolysaccharidesMaleRandom AllocationAnti-Bacterial AgentsDexamethasoneEnrofloxacinLipopolysaccharidesBuffalo calvesDexamethasoneEnrofloxacinMPCPK–PD modelingTime-kill kinetics

Identifiers

PMID31701397
OpenAlexW2988531749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.