Evidence map›Paper›PMID 31701386›Full record

ArticleLasers in medical science2020

The influence of morphological distribution of melanin on parameter selection in laser thermotherapy for vascular skin diseases.

Z X Ying, Y B Zhao, D Li, Y L Shang, B Chen, W C Jia

Abstract read
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In one paragraph

Article in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Z X YingDepartment of Dermatology, the Second Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China.
Y B ZhaoState Key Laboratory of Multiphase Flow in Power Engineering, Xi'an Jiaotong University, Xi'an, 710069, Shaanxi, China.
D LiState Key Laboratory of Multiphase Flow in Power Engineering, Xi'an Jiaotong University, Xi'an, 710069, Shaanxi, China. lidong@mail.xjtu.edu.cn.ORCID http://orcid.org/0000-0003-3172-3853
Y L ShangState Key Laboratory of Multiphase Flow in Power Engineering, Xi'an Jiaotong University, Xi'an, 710069, Shaanxi, China.
B ChenState Key Laboratory of Multiphase Flow in Power Engineering, Xi'an Jiaotong University, Xi'an, 710069, Shaanxi, China. chenbin@mail.xjtu.edu.cn.
W C JiaBeckman Laser Institution and Medical Clinic, University of California, Irvine, 92697, CA, USA.
Xi'an Jiaotong University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CNUniversity of California, Irvine · US

Funding

International Science & Technology Cooperation Plan of Shaanxi Province 2016KW-024National Natural Science Foundation of China 51727811National Natural Science Foundation of China 51976170
6 · The paper itself

Abstract

Port wine stains (PWSs) are congenital vascular malformations that progressively darken and thicken with age. Currently, laser therapy is the most effective way in clinical management of PWS. It is known that skin pigmentation (melanin content) affects the radiant exposure that can be safely applied to treat PWS. However, the effect of melanin distribution in the epidermis on the maximum safe radiant exposure has not been studied previously. In this study, 10 different morphological distributions of melanin were proposed according to the formation and migration characteristics of melanin, and the two-scale heat transfer model was employed to investigate the influence of melanin distribution on the threshold radiant exposure of epidermis and blood vessels. The results show that melanin distributions do have a strong effect on laser parameter selection. When uniform melanin distribution is assumed, the threshold radiant exposure to damage a typical PWS blood vessel (50 μm diameter) is 8.62 J/cm

Indexed as

Hyperthermia, InducedLaser TherapyBlood VesselsEpidermisHumansMelaninsModels, BiologicalSkin Diseases, VascularTemperatureMelaninsCryogen spray coolingLaser treatmentMelanin distributionPort wine stainsTwo-scale model

Identifiers

PMID31701386
OpenAlexW2988766981

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.