Evidence map›Paper›PMID 31701329›Full record

ArticleJournal of neurology2020

Symptomatic carotid near-occlusion causes a high risk of recurrent ipsilateral ischemic stroke.

Thomas Gu, Richard I Aviv, Allan J Fox, Elias Johansson

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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  11. Prevalence and Incidence of Carotid-Fetal-Posterior Syndrome.Cerebrovascular diseases (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Thomas GuDepartment of Clinical Science, Umeå University, Norrlands Universitetssjukhus, 907 37, Umeå, Sweden. thomas.gu@umu.se.ORCID http://orcid.org/0000-0002-0560-3578
Richard I AvivDepartment of Medical Imaging, Sunnybrook Health Science Center, University of Toronto, Toronto, Canada.
Allan J FoxEmeritus, Department of Medical Imaging, Sunnybrook Health Science Center, University of Toronto, Toronto, Canada.
Elias JohanssonDepartment of Clinical Science, Umeå University, Norrlands Universitetssjukhus, 907 37, Umeå, Sweden.
Sunnybrook Health Science Centre · CAUniversity Hospital of Umeå · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the risk of recurrent ipsilateral ischemic stroke in patients with symptomatic near-occlusion with and without full collapse.

methodsIncluded were consecutive patients eligible for revascularization, grouped into symptomatic conventional ≥ 50% carotid stenosis (n = 266), near-occlusion without full collapse (n = 57) and near-occlusion with full collapse (n = 42). The risk of preoperative recurrent ipsilateral ischemic stroke was analyzed, or, for cases not revascularized within 90 days, 90-day risk was analyzed.

resultsThe risk of a preoperative recurrent ipsilateral ischemic stroke or ipsilateral retinal artery occlusion was 15% (95% CI 9-20%) for conventional ≥ 50% stenosis, 22% (95% CI 6-38%) among near-occlusion without full collapse and 30% (95% CI 16-44%) among near-occlusion with full collapse (p = 0.01, log rank test). In multivariate analysis, near-occlusion with full collapse had a higher risk of recurrent ipsilateral ischemic stroke (adjusted HR 2.6, 95% CI 1.3-5.3) and near-occlusion without full collapse tended to have a higher risk (adjusted HR 2.0, 95% CI 0.9-4.5) than conventional ≥ 50% stenosis. Only 24% of near-occlusion with full collapse underwent revascularization, common causes for abstaining were misdiagnosis as occlusion (31%), deemed surgically unfeasible (21%) and low perceived benefit (10%).

conclusionsSymptomatic carotid near-occlusion has a high short-term risk of recurrent ipsilateral ischemic stroke, especially near-occlusion with full collapse.

Indexed as

Cerebral RevascularizationAgedAged, 80 and overBrain IschemiaCarotid StenosisCerebral AngiographyComputed Tomography AngiographyFemaleHumansMaleMiddle AgedRecurrenceRetinal Artery OcclusionRiskStrokeCarotid stenosisLarge vessel diseaseNeurologyStroke

Identifiers

PMID31701329
PMCPMC6989616
OpenAlexW2986678710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.