Evidence map›Paper›PMID 31701311›Full record

ReviewAnnals of biomedical engineering2020

Biomaterials and Contraception: Promises and Pitfalls.

Isabella Claure, Deborah Anderson, Catherine M Klapperich, Wendy Kuohung, Joyce Y Wong

Open access · greenAbstract readReview
In one paragraph

Review in Annals of biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Toward Sex-Specific Biomaterials Innovation: A Perspective.ACS biomaterials science & engineering · 2025
    Review
  2. Article
  3. Review
  4. Review
  5. Bioengineering Approaches for Placental Research.Annals of biomedical engineering · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Isabella ClaureDepartments of Biomedical Engineering, Boston University, Boston, MA, 02215, USA.
Deborah AndersonObstetrics and Gynecology, Boston University, Boston, MA, 02215, USA.
Catherine M KlapperichDepartments of Biomedical Engineering, Boston University, Boston, MA, 02215, USA.
Wendy KuohungObstetrics and Gynecology, Boston University, Boston, MA, 02215, USA.
Joyce Y WongDepartments of Biomedical Engineering, Boston University, Boston, MA, 02215, USA. jywong@bu.edu.ORCID http://orcid.org/0000-0002-3526-6381
Boston University · US

Funding

Project 3: Film Formulation, PK/PD and Safety Studies of ZB-06P50HD096957 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ANDERSON, DEBORAH J, WHALEY, KEVIN · 2019 to 2025
$12.9M
PediaTrac: Web-based measure to screen and track early developmental trajectoriesR01HD095957 · NICHD · EASTERN MICHIGAN UNIVERSITY · PI HUTH-BOCKS, ALISSA, LAJINESS-O'NEILL, RENÉE ROCHELLE · 2018 to 2022
$4.4M
Translational Research in BiomaterialsT32EB006359 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MARK W. GRINSTAFF, Michelle H Teplensky · 2009 to 2026
$4.2M
Preclinical Testing of Human Contraceptive Antibody (HCA) and HCA productsU54HD096957 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ANDERSON, DEBORAH J, MOENCH, THOMAS RAY · 2018 to 2018
$2.0M
National Institutes of Health (US) U54 HD095957NIBIB NIH HHS T32 EB006359NICHD NIH HHS R01 HD095957NICHD NIH HHS U54 HD096957NIH HHS T32 EB006359
6 · The paper itself

Abstract

The present state of reproductive and sexual health around the world reveals disparities in contraceptive use and effectiveness. Unintended pregnancy and sexually transmitted infection transmission rates remain high even with current prevention methods. The 20th century saw a contraceptive revolution with biomedical innovation driving the success of new contraceptive technologies with central design concepts and materials. Current modalities can be broadly categorized according to their mode of function: reversible methods such as physical/chemical barriers or hormonal delivery devices via systemic (transdermal and subcutaneous) or localized (intrauterine and intravaginal) administration, and nonreversible sterilization procedures such as tubal ligation and vasectomy. Contraceptive biomaterials are at present dominated by well-characterized elastomers such as polydimethylsiloxane and ethylene vinyl acetate due to their favorable material properties and versatility. Contraceptives alter the normal function of cellular components in the reproductive systems to impair fertility. The purpose of this review is to highlight the bioengineering design of existing methods, explore novel adaptations, and address notable shortcomings in current contraceptive technologies.

Indexed as

Biocompatible MaterialsBioengineeringContraceptionContraceptive AgentsDrug Delivery SystemsHumansBiocompatible MaterialsContraceptive AgentsBarrier technologiesBioengineering designHormonal delivery devicesReproductive healthSTI prevention

Identifiers

PMID31701311
PMCPMC7202983
OpenAlexW2988401510

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.