SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
Systematic review and meta-analysis of imaging characteristics in Chiari I malformation: does anything really matter?
Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Preoperative radiological scoring system in Chiari malformation type 1: a surgical guide.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Long-term outcomes following posterior fossa decompression in pediatric patients with Chiari malformation type 1, a population-based cohort study.Acta neurochirurgica · 2024Article
- Predictors of syrinx presentation and outcomes in pediatric Chiari malformation type I: a single institution experience of 218 consecutive syrinx patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Craniocervical Morphometry in Pomeranians-Part II: Associations with Chiari-like Malformation and Syringomyelia.Animals : an open access journal from MDPI · 2024Article
- Chiari Type 1 Malformation and Syringomyelia in Children: Classification and Treatment Options.Advances and technical standards in neurosurgery · 2023Review
- Use of Intraoperative Neuromonitoring in Surgical Treatment of Acute Presentation of Chiari I Malformation: A Case Report.Journal of neurological surgery reports · 2023Article
- Pediatric Chiari I malformation: novel and traditional measurements associated with syrinx and surgery.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- A Clinical Study on the Treatment of Recurrent Chiari (Type I) Malformation with Syringomyelia Based on the Dynamics of Cerebrospinal Fluid.BioMed research international · 2022Article
- Preoperative measurements on MRI in Chiari 1 patients fail to predict outcome after decompressive surgery.Acta neurochirurgica · 2021Article
- Natural History and Conservative Treatment Options in Chiari Malformation Type I in Adults: A Literature Update.Cureus · 2020Review
- Pulsatile cerebrospinal fluid dynamics in Chiari I malformation syringomyelia: Predictive value in posterior fossa decompression and insights into the syringogenesis.Journal of craniovertebral junction & spineArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrevious studies have attempted to evaluate the utility of preoperative magnetic resonance imaging (MRI) parameters in predicting outcomes in Chiari I malformation. We performed a systematic review and meta-analysis to determine what preoperative imaging features (if any) predict (1) presence of preoperative symptoms or associated findings, (2) need for surgical decompression, or (3) improvement after surgical decompression.
methodsAll publications through June 2018 on PubMed, Embase, and Cochrane Library databases were searched using the keywords "Chiari I malformation" AND "decompression" OR "imaging." One thousand two hundred ten publications were identified, and 20 were included for our systematic review; nine were included in the meta-analysis.
resultsTonsil position, clivus gradient, and scoliotic curve of > 20° were all associated with the presence of preoperative syrinx. Degree of scoliotic curve was associated with length of syrinx. Pre-operative findings of central syrinx morphology, shorter syrinx, and scoliotic curve < 20° were associated with post-operative stability/improvement. Post-operative symptomatic improvement was associated with preoperative pB-C2 line ≥ 3 mm, absence of scoliosis, and presence of syrinx. By meta-analysis, there was no significant difference in post-operative improvement between patients with and without syrinx (OR = 0.89; 95% CI 0.58-1.37). Meta-analysis showed no significant difference in post-operative improvement between patients with and without basilar invagination (OR = 1.31; 95% CI 0.72-2.36).
conclusionsMultiple studies have attempted to identify preoperative imaging parameters to predict post-operative improvement, but no consistently reliable criteria have been defined. This review and meta-analysis highlight the importance of considering each patient's clinical history and physical exam within the context of associated radiographic abnormalities.
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