ArticleDigestive diseases and sciences2020
Updated Assessment of Colorectal Cancer Incidence in the U.S. by Age, Sex, and Race/Ethnicity.
Article in Digestive diseases and sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of methods to estimate colorectal cancer incidence using population-based cancer registries.BMC medical research methodology · 2022Pooled it
- Statistical methods for measuring trends in colorectal cancer incidence in registries: A systematic review.Frontiers in oncology · 2022Pooled it
- Unraveling RELA as a potential dioctyl terephthalate-related target regulates M2-like macrophages to induce an immunosuppressive microenvironment in colorectal cancer: a multi-omics data study by experimental validation.Molecular diversity · 2026Article
- Integrated muti-omics data and machine learning reveal CD151 as a key biomarker inducing chemoresistance in metabolic syndrome-related early-onset left-sided colorectal cancer.Functional & integrative genomics · 2025Article
- Targeting signaling pathways with andrographolide in cancer therapy (Review).Molecular and clinical oncology · 2024Review
- Colorectal Cancer Incidence in Iran Based on Sex, Age, and Geographical Regions: A Study of 2014-2017 and Projected Rates to 2025.Archives of Iranian medicine · 2024Article
- Standardization of Colon Resection for Cancer: An Overview of the American College of Surgeons Commission on Cancer Standard 5.6.Annals of surgical oncology · 2024Article
- Impact of race-specific screening guideline on the uptake of colorectal cancer screening among young African Americans.Cancer medicine · 2022Article
- Article
- Colon Cancer: From Epidemiology to Prevention.Metabolites · 2022Review
- Opportunities for personalizing colorectal cancer care: an analysis of SEER-medicare data.The pharmacogenomics journal · 2022Article
- New considerations for colorectal cancer screening based on the demographic profile of colorectal cancer in a Greek population.Molecular and clinical oncology · 2022Article
- Article
- Review
- A National Study of Colorectal Cancer Survivorship Disparities: A Latent Class Analysis Using SEER (Surveillance, Epidemiology, and End Results) Registries.Frontiers in public health · 2021Article
- Inverted Yield Curve: The Alarming Rising Incidence of CRC in Young People.Digestive diseases and sciences · 2020Article
- Racial and Ethnic Disparities in Colorectal Cancer Incidence Trends Across Regions of the United States From 2001 to 2020 - A United States Cancer Statistics Analysis.Cancer control : journal of the Moffitt Cancer CenterArticle
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether recent updates to colon cancer screening guidelines benefit men and women or all race/ethnic groups equally is not clear.
aimsThe aim of this study is to evaluate age-, sex-, and race/ethnicity-specific trends in CRC incidence and disease burden among adults.
methodsUsing 2000-2014 surveillance, epidemiology, and end results database, annual CRC incidence (per 100,000 persons/year) among U.S. adults was categorized by age (using 10-year age intervals) and stratified by sex and race/ethnicity. Comparison of incidence between groups utilized the z-statistic with p < 0.05 indicating statistical significance.
resultsOverall, CRC incidence was the highest among patients aged ≥ 80 years (330.8 per 100,000 persons/year), which was significantly higher in men versus women (377.2 vs. 304.3 per 100,000 persons/year, p < 0.001). CRC incidence in younger individuals was 22.8 per 100,000 persons/year (age 40-49) and 6.8 per 100,000 persons/year (age 30-39). CRC incidence was significantly higher in African Americans compared to non-Hispanic whites. From 2000 to 2014, CRC incidence declined in all age groups over age 60, remained stable in age 50-59, and demonstrated proportional increases in among age 20-49 years. While CRC incidence in all race/ethnic groups aged ≥ 60 years declined, Hispanics aged 50-59 increased 21.9%, but remained stable in other race/ethnic groups. Race/ethnicity-specific disparities in CRC incidence in patients aged 20-49 were also observed.
conclusionsWhile CRC incidence has declined among U.S. adults aged ≥ 60, increasing incidence among patients aged < 50 is concerning. Identifying risk factors among "average-risk" patients is needed to better implement targeted screening of individuals not currently meeting CRC screening criteria.
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