ReviewCurrent psychiatry reports2019
Effects of Hormonal Contraceptives on Mood: A Focus on Emotion Recognition and Reactivity, Reward Processing, and Stress Response.
Review in Current psychiatry reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- Evidence-Based Recommendations for the Pharmacological Treatment of Women with Schizophrenia Spectrum Disorders.Current psychiatry reports · 2023Pooled it
- Empathic Accuracy and Behavioral Empathy After a Moderate Dose of Beer.Human psychopharmacology · 2026Trial
- Triple network model of brain connectivity changes related to adverse mood effects in an oral contraceptive placebo-controlled trial.Translational psychiatry · 2023Trial
- Hormonal Medication Effects on Trichotillomania and Skin Picking Disorder.Life (Basel, Switzerland) · 2026Article
- Hormonal contraception and mental health: a narrative review of screening, monitoring, and patient-centered care for family physicians.Frontiers in psychiatry · 2026Review
- Depression across the menopausal stages in the United Arab Emirates: prevalence and risk factors.Frontiers in global women's health · 2026Article
- Research Review: Are sampling biases masking long-term effects of hormonal contraceptive use in adolescence on risk for depression?Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- Effect of combined oral contraceptive use on verbal memory function in healthy women.Archives of women's mental health · 2025Article
- Muscular Performance Is Not Significantly Altered Throughout Phases of the Menstrual Cycle or a Hormonal Contraceptive Cycle in Collegiate Softball Players.Muscles (Basel, Switzerland) · 2025Article
- 28 days later: A prospective daily study on psychological well-being across the menstrual cycle and the effects of hormones and oral contraceptives.Psychological medicine · 2025Article
- Depression and Its Associated Factor Among Women Using Hormonal Contraceptives: A Cross-Sectional Study in Jimma Town Public Health Facilities, Southwest Ethiopia, 2022.Women's health reports (New Rochelle, N.Y.) · 2025Article
- Hormonal contraceptive use is associated with reduced central serotonergic activity indexed by the loudness dependence of auditory evoked potentials.Frontiers in human neuroscience · 2025Article
- Loudness dependence of the auditory evoked potential: temporal stability, associations to sociodemographic variables, and functional significance-implications for clinical research.Frontiers in human neuroscience · 2025Article
- Beyond Birth Control: The Neuroscience of Hormonal Contraceptives.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- The Most Common Side Effects, Concerns and Discontinuation Patterns of Oral Contraceptive Pills Among Polish Women: A Cross-Sectional Study.Journal of family & reproductive health · 2024Article
- PACAP-38 and sex hormones in women with migraine: exploratory analysis of a cross-sectional, matched cohort study.The journal of headache and pain · 2024Article
- Amphetamine use disorder is associated with striatum hypoactivation during anticipation of loss and reward.Journal of psychopharmacology (Oxford, England) · 2024Article
- Depression in Women: Potential Biological and Sociocultural Factors Driving the Sex Effect.Neuropsychobiology · 2024Review
- A citizen-science-enabled catalogue of the vaginal microbiome and associated factors.Nature microbiology · 2023Article
- Mental Health Symptoms in Oral Contraceptive Users During Short-Term Hormone Withdrawal.JAMA network open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewWe review recent research investigating the relationship of hormonal contraceptives and mood with a focus on relevant underlying mechanisms, such as emotion recognition and reactivity, reward processing, and stress response. RECENT
findingsAdverse effects of hormonal contraceptives (HCs) on mood seem most consistent in women with a history of depressive symptoms and/or previous negative experience with HC-intake. Current evidence supports a negativity bias in emotion recognition and reactivity in HC-users, although inconsistent to some extent. Some data, however, do indicate a trend towards a blunted reward response and a potential dysregulation of the stress response in some HC-users. HC-effects on psychological and neurophysiological mechanisms underlying mood are likely context-dependent. We provide suggestions on how to address some of the contributing factors to this variability in future studies, such as HC-dose, timing, administration-mode, and individual risk. A better understanding of how and when HCs affect mood is critical to provide adequate contraceptive choices to women worldwide.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.