Evidence map›Paper›PMID 31701122›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2020

Reinstatement of Event Details during Episodic Simulation in the Hippocampus.

Preston P Thakral, Kevin P Madore, Donna Rose Addis, Daniel L Schacter

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Episodic recombination and the role of time in mental travel.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  5. Constructive Memory and Conscious Experience.Journal of cognitive neuroscience · 2024
    Article
  6. Article
  7. Article
  8. Concepts as plug & play devices.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  9. Article
  10. The hippocampal formation and action at a distance.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  11. Evolution, Emotion, and Episodic Engagement.The American journal of psychiatry · 2021
    Review
  12. Article
  13. The Ventral and Dorsal Default Mode Networks Are Dissociably Modulated by the Vividness and Valence of Imagined Events.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  14. Concept formation as a computational cognitive process.Current opinion in behavioral sciences · 2021
    Article
  15. Dynamic Content Reactivation Supports Naturalistic Autobiographical Recall in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  16. Modulation of hippocampal brain networks produces changes in episodic simulation and divergent thinking.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Preston P ThakralDepartment of Psychology, Harvard University, Cambridge, MA 02138, USA.
Kevin P MadoreDepartment of Psychology, Stanford University, Stanford, CA 94305, USA.
Donna Rose AddisRotman Research Institute, Baycrest Health Sciences, Toronto, ON M6A 2E1, Canada.
Daniel L SchacterDepartment of Psychology, Harvard University, Cambridge, MA 02138, USA.

Funding

EVENT RELATED NEUROIMAGING OF HUMAN MEMORY FORMATIONR01MH060941 · NIMH · HARVARD UNIVERSITY · PI SCHACTER, DANIEL L · 2000 to 2025
$9.5M
Upgrade Siemens MAGNETOM Trio to MAGNETOM Prisma Fit 3T Human MRI SystemS10OD020039 · OD · HARVARD UNIVERSITY · PI BUCKNER, RANDY L · 2015 to 2015
$600k
Interactions between goals, attention, and memory in younger and older adultsF32AG059341 · NIA · STANFORD UNIVERSITY · PI MADORE, KEVIN PAUL · 2018 to 2021
$222k
NIA NIH HHS F32 AG059341NIH HHS S10 OD020039NIMH NIH HHS R01 MH060941
6 · The paper itself

Abstract

According to the constructive episodic simulation hypothesis, episodic simulation (i.e., imagining specific novel future episodes) draws on some of the same neurocognitive processes that support episodic memory (i.e., recalling specific past episodes). Episodic retrieval supports the ability to simulate future experiences by providing access to episodic details (e.g., the people and locations that comprise memories) that can be recombined in new ways. In the current functional neuroimaging study, we test this hypothesis by examining whether the hippocampus, a region implicated in the reinstatement of episodic information during memory, supports reinstatement of episodic information during simulation. Employing a multivoxel pattern similarity analysis, we interrogated the similarity between hippocampal neural patterns during memory and simulation at the level of individual event details. Our findings indicate that the hippocampus supports the reinstatement of detail-specific information from episodic memory during simulation, with the level of reinstatement contributing to the subjective experience of simulated details.

Indexed as

Memory, EpisodicAdolescentAdultFemaleHippocampusHumansMaleMental RecallYoung Adultepisodic memoryimaginingMVPAparietalrecollection

Identifiers

PMID31701122
PMCPMC7174999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.