Evidence map›Paper›PMID 31701094›Full record

ArticleFood chemistry: X2019

Diversely positive-charged gold nanoparticles based biosensor: A label-free and sensitive tool for foodborne pathogen detection.

Tong Bu, Pei Jia, Jinghan Liu, Yingnan Liu, Xinyu Sun, Meng Zhang, Yongming Tian, Daohong Zhang, Jianlong Wang, Li Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  15. Microbial biosensors for recreational and source waters.Journal of microbiological methods · 2020
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tong BuCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Pei JiaCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Jinghan LiuCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Yingnan LiuCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Xinyu SunCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Meng ZhangCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Yongming TianCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Daohong ZhangCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Jianlong WangCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Li WangCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoparticles (AuNPs)-based lateral flow strip (LFS) enables a quick screening of foodborne bacteria in point-of-care (POC) diagnostics but suffers from the cumbersome labeling of antibodies and poor sensitive performance. Here, we innovated a label-free immunoassay to detect pathogenic bacteria by introducing diversely positive charges functionalized AuNPs ((+) AuNPs). The (+) AuNPs can be loaded on negatively charged bacteria via electrostatic interaction, leading to a color labeling to target bacteria. Afterward, the (+) AuNPs-bacteria complex can be specifically captured by monoclonal antibody (McAb) immobilized on test (T)-line. Under optimum conditions, the proposed LFS exhibited a lowest detectable concentration of 10

Indexed as

Escherichia coli O157Label-freeLateral flow stripPositively charged AuNPsSalmonella enteritidisSensitive detection

Identifiers

PMID31701094
PMCPMC6831733

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.