Evidence map›Paper›PMID 31701026›Full record

ArticleCommunications biology2019

Static magnetic field stimulation of the supplementary motor area modulates resting-state activity and motor behavior.

José A Pineda-Pardo, Ignacio Obeso, Pasqualina Guida, Michele Dileone, Bryan A Strange, José A Obeso, Antonio Oliviero, Guglielmo Foffani

Registry-linked trialOpen access · goldAbstract readControlled Clinical Trial
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06840678 (Patogénesis Cortical De La Enfermedad De Parkinson), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06840678 phase1unknown statusnot on this mapstarted 2022, after this paper: background citation

Patogénesis Cortical De La Enfermedad De Parkinson: Efectos Corticales Y Corticoestriatales De La Estimulación Transcraneal Por Campo Magnético Estático En Pacientes Con Enfermedad De Parkinson

TypeinterventionalSponsorFundación de investigación HMRan2022 to 2025Enrolled20ConditionsParkinson's DiseaseArmsTranscranial static magnetic field stimulation (tSMS) of the supplementary motor area
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
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  5. Review
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  11. Noninvasive modulation of human corticostriatal activity.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Article
  13. Article
  14. Safety for Human MR Scanners at 7T.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

José A Pineda-Pardo *1CINAC, Hospital Universitario HM Puerta del Sur, Móstoles, Universidad CEU-San Pablo, Madrid, Spain.ORCID 0000-0002-8776-0031
Ignacio Obeso *1CINAC, Hospital Universitario HM Puerta del Sur, Móstoles, Universidad CEU-San Pablo, Madrid, Spain.
Pasqualina Guida1CINAC, Hospital Universitario HM Puerta del Sur, Móstoles, Universidad CEU-San Pablo, Madrid, Spain.
Michele Dileone1CINAC, Hospital Universitario HM Puerta del Sur, Móstoles, Universidad CEU-San Pablo, Madrid, Spain.
Bryan A Strange2Laboratory for Clinical Neuroscience, CTB, Universidad Politecnica de Madrid, Madrid, Spain.ORCID 0000-0001-6476-4091
José A Obeso1CINAC, Hospital Universitario HM Puerta del Sur, Móstoles, Universidad CEU-San Pablo, Madrid, Spain.
Antonio Oliviero5Hospital Nacional de Parapléjicos, Toledo, Spain.
Guglielmo Foffani1CINAC, Hospital Universitario HM Puerta del Sur, Móstoles, Universidad CEU-San Pablo, Madrid, Spain.ORCID 0000-0001-7289-6668
Universidad San Pablo CEU · ESFundacion Centro De Investigacion De Enfermedades Neurologicas · ESHospital Nacional de Parapléjicos · ESUniversity Hospital HM Puerta del Sur · ES

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

Focal application of a strong static magnetic field over the human scalp induces measurable local changes in brain function. Whether it also induces distant effects across the brain and how these local and distant effects collectively affect motor behavior remains unclear. Here we applied transcranial static magnetic field stimulation (tSMS) over the supplementary motor area (SMA) in healthy subjects. At a behavioral level, tSMS increased the time to initiate movement while decreasing errors in choice reaction-time tasks. At a functional level, tSMS increased SMA resting-state fMRI activity and bilateral functional connectivity between the SMA and both the paracentral lobule and the lateral frontotemporal cortex, including the inferior frontal gyrus. These results suggest that tSMS over the SMA can induce behavioral aftereffects associated with modulation of both local and distant functionally-connected cortical circuits involved in the control of speed-accuracy tradeoffs, thus offering a promising protocol for cognitive and clinical research.

Indexed as

AdultCross-Over StudiesDouble-Blind MethodFemaleFunctional NeuroimagingHealthy VolunteersHumansMagnetic Resonance ImagingMaleModels, NeurologicalMotor ActivityMotor CortexRestTranscranial Magnetic StimulationYoung AdultDecisionMagnetic resonance imagingMotor cortexTranscranial magnetic stimulation

Identifiers

PMID31701026
PMCPMC6823375
OpenAlexW2982417117

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.