ArticleInternational journal of women's dermatology2019
Sex differences in the prevalence of vascular disease and risk factors in young hospitalized patients with psoriasis.
Article in International journal of women's dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Epidemiology of Hypertension in Psoriasis: An Analysis of Trends from 2006 to 2023.Psoriasis (Auckland, N.Z.) · 2025Review
- Exploring the Link Between Genetic Predictors of Cardiovascular Disease and Psoriasis.JAMA cardiology · 2024Article
- Comparison of metabolic and neurological comorbidities in Asian patients with psoriasis and atopic dermatitis.Scientific reports · 2024Article
- Traditional and Non-traditional Cardiovascular Risk Factors and Cardiovascular Disease in Women with Psoriasis.Acta dermato-venereologica · 2022Article
- Cardiovascular comorbidities in psoriasis (Review).Experimental and therapeutic medicine · 2022Review
- Aging in psoriasis vulgaris: female patients are epigenetically older than healthy controls.Immunity & ageing : I & A · 2021Article
- Characterization of PCSK9 in the Blood and Skin of Psoriasis.The Journal of investigative dermatology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPsoriasis is an inflammatory skin disease associated with atherosclerotic cardiovascular disease (ASCVD) risk factors and vascular disease. The relative impact of psoriasis on vascular disease is the strongest in young patients with psoriasis, yet data are lacking on how sex differences influence cardiovascular risk factors and vascular disease in these patients.
objectiveThis observational study aimed to identify the burden of cardiovascular risk factors and vascular disease in patients with psoriasis and to explore whether this burden is different between men and women age < 35 years.
methodsYoung (age ≥ 20 and < 35 years) hospitalized patients with psoriasis from the United States National Inpatient Sample were compared with those matched patients without psoriasis. Vascular disease was defined as ASCVD and/or venous thromboembolic disease. Multivariable logistic regression was used to determine the associations between psoriasis, sex, ASCVD risk factors, and vascular disease.
resultsOverall, patients with psoriasis (n = 18,353) were more often obese (16% vs. 6%); smokers (31% vs. 17%); and diagnosed with diabetes mellitus (10% vs. 6%), hypertension (16% vs. 8%), hyperlipidemia (6% vs. 2%), ASCVD (2.2% vs. 1.6%), and deep vein thrombosis (6% vs. 4%; all p < .001) compared with patients without psoriasis (n = 55,059; matched by age, sex, and race). When stratified by sex, women with psoriasis were more likely to have multiple cardiovascular risk factors and ASCVD (odds ratio: 2.6; 95% confidence interval [2.1-3.1]) compared with men with psoriasis (odds ratio: 1.2; 95% confidence interval [0.9-1.4]; interaction p < .01). The association between psoriasis and ASCVD in women remained unchanged after multivariable adjustment for traditional cardiovascular risk factors.
conclusionPsoriasis was associated with cardiovascular disease and risk factors in young hospitalized patients, with stronger associations among women than among men.
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