Evidence map›Paper›PMID 31700920›Full record

ArticleAnnals of translational medicine2019

The prognostic significance of co-existence ductal carcinoma

Hongliang Chen, Fang Bai, Maoli Wang, Mingdi Zhang, Peng Zhang, Kejin Wu

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  4. Prognostic significance of ductal carcinomaMolecular and clinical oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hongliang ChenDepartment of Breast Surgery, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
Fang BaiDepartment of Breast Surgery, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
Maoli WangDepartment of Breast Surgery, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
Mingdi ZhangDepartment of Breast Surgery, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
Peng ZhangDepartment of Breast Surgery, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
Kejin WuDepartment of Breast Surgery, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
Obstetrics and Gynecology Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the prognostic significance of co-existence ductal carcinoma in situ (DCIS) in invasive ductal breast cancer (IDC) compared with pure IDC.

methodsThe Surveillance, Epidemiology, and End Results (SEER) database was searched to identify unilateral IDC cases between 2004 and 2015, which were grouped into pure IDC and IDC with DCIS component (IDC-DCIS). Comparisons of the distribution of clinical-pathological characteristics the two groups were performed using Pearson's chi-square. Breast cancer-specific survival (BCSS) and overall survival (OS) were estimated using the Kaplan-Meier method and compared across RS groups using the log-rank statistic. Cox models were fitted to assess the factors independently associated with survival. A 1:1 matched case-control analysis was conducted with each clinical-pathological characteristic matched completely.

resultsA total of 98,097 pure IDC cases (39.6%) and 149,477 IDC-DCIS cases (60.4%) were enrolled. IDC-DCIS patients were presented with less aggressive characteristics such as lower proportion of histologic grade III (34.2%

conclusionsCo-existence DCIS showed quite different prognostic significance among ER positive and negative disease.

Indexed as

case-controlco-existenceductal carcinoma in situ (DCIS)Invasive ductal breast cancer (IDC)population-basedprognosis

Identifiers

PMID31700920
PMCPMC6803232
OpenAlexW2970355754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.