ArticleAnnals of translational medicine2019
The alterations of gut microbiota in mice with chronic pancreatitis.
Article in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Polysaccharide from Asimina triloba fruits alleviates DSS-induced ulcerative colitis by modulating inflammatory signaling and gut microbiota.NPJ science of food · 2025Article
- Metagenomics reveals functional profiles of gut microbiota during the recovery phase of acute pancreatitis.Scientific reports · 2025Article
- Statin therapy associated Lactobacillus intestinalis attenuates pancreatic fibrosis through remodeling intestinal homeostasis.NPJ biofilms and microbiomes · 2025Article
- Dysregulation of the microbiota-gut-brain axis induced by chronic pancreatitis mediates anxiety- and depression-like behaviors in mice.Frontiers in immunology · 2025Article
- Review
- Gut microbiota-derived metabolites tune host homeostasis fate.Seminars in immunopathology · 2024Review
- Bibliometric analysis of pancreatic diseases and gut microbiota research from 2002 to 2022.Heliyon · 2024Article
- Traditional pediatric massage enhanced the skeletal muscle mass in OVA-exposed adolescent rats via regulating SCFAs-FFAR2-IGF-1/AKT pathway.Frontiers in microbiology · 2024Article
- Gut microbiota controls the development of chronic pancreatitis: A critical role of short-chain fatty acids-producing Gram-positive bacteria.Acta pharmaceutica Sinica. B · 2023Article
- Altered glucose metabolism and its association with carbonic anhydrase 8 in Machado-Joseph Disease.Metabolic brain disease · 2022Article
- Brief Hydromorphone Exposure During Pregnancy Sufficient to Induce Maternal and Neonatal Microbial Dysbiosis.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2022Article
- Gut microbiota and BMI throughout childhood: the role of firmicutes, bacteroidetes, and short-chain fatty acid producers.Scientific reports · 2022Article
- Comprehensive Analysis of the Relationships Between the Gut Microbiota and Fecal Metabolome in Individuals With Primary Sjogren's Syndrome by 16S rRNA Sequencing and LC-MS-Based Metabolomics.Frontiers in immunology · 2022Article
- Chronic pancreatitis in a caerulein-induced mouse model is associated with an altered gut microbiome.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2022Article
- Gut Dysbiosis in Pancreatic Diseases: A Causative Factor and a Novel Therapeutic Target.Frontiers in nutrition · 2022Review
- Sodium Butyrate Attenuates Taurocholate-Induced Acute Pancreatitis by Maintaining Colonic Barrier and Regulating Gut Microorganisms in Mice.Frontiers in physiology · 2022Article
- Gut microbiota in pancreatic diseases: possible new therapeutic strategies.Acta pharmacologica Sinica · 2021Review
- Characteristics of Gut Microbiota in Cerulein-Induced Chronic Pancreatitis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Microbial Characteristics and Safety of Dairy Manure ComPosting for Reuse as Dairy Bedding.Biology · 2020Article
- Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis.Cell death & disease · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe changes of intestinal microbiome are associated with inflammatory, metabolic, and malignant disorders, and there are no studies assessing the intestinal microbiota of mice with chronic pancreatitis (CP). Thus, we aim to investigate the variations in diversity, composition and function of intestinal microbiota in CP mice.
methodsSixteen male C57BL/6 mice were randomly selected, and divided into two groups, treated intraperitoneally with saline (normal control group, CT group) or ethanol + cerulein (experimental group, CP group) for 6 weeks. Body weight as measured in entire processes. Histopathological examination of CP index was conducted to verify the CP induction. Extracted DNA from colon samples was used for Illumina HiSeq sequencing of the bacterial V4 region of 16S rRNA gene and analyzed using Quantitative Insights Into Microbial Ecology (QIIME). Functional profiling of microbial communities was predicted with BugBase.
resultsSignificant alterations of the gut microbiota were found in the CP mice compared to CT groups, as revealed by significant decrease in bacterial richness and diversity, declined the relative abundance of
conclusionsThis study indicated that mice with CP had a distinct microbiota profile.
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