Evidence map›Paper›PMID 31700667›Full record

ArticleJournal of virus eradication2019

Persistence of HIV reservoir following successful haematopoietic stem cell transplant for juvenile myelomonocytic leukaemia in a child with perinatally acquired HIV.

G Dobson, N Klein, P Veys, W Qasim, J Silva, I L Cheng, D Shingadia, G Tudor-Williams, S A Watters, H Lyall and 3 more

Open access · goldAbstract readEditorial
PubMed Full text at PMC
In one paragraph

Article in Journal of virus eradication, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

G DobsonPaediatric Infectious Diseases Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
N KleinPaediatric Infectious Diseases Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
P VeysUCL Great Ormond Street Institute of Child Health, London, UK.
W QasimUCL Great Ormond Street Institute of Child Health, London, UK.
J SilvaPaediatric Bone Marrow Transplant Department, Great Ormond Street Hospital NHS Foundation Trust, London, UK.
I L ChengPaediatric Pharmacy Department, Great Ormond Street Hospital NHS Foundation Trust, London, UK.
D ShingadiaPaediatric Infectious Diseases Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
G Tudor-WilliamsPaediatric Infectious Diseases Department, St Mary's Hospital, Imperial College Healthcare NHS Foundation Trust, London, UK.
S A WattersUCL Great Ormond Street Institute of Child Health, London, UK.
H LyallPaediatric Infectious Diseases Department, St Mary's Hospital, Imperial College Healthcare NHS Foundation Trust, London, UK.
A RaoPaediatric Haematology Department, Great Ormond Street Hospital NHS Foundation Trust, London, UK.
C FosterPaediatric Infectious Diseases Department, St Mary's Hospital, Imperial College Healthcare NHS Foundation Trust, London, UK.
A BamfordPaediatric Infectious Diseases Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Great Ormond Street Hospital for Children NHS Foundation Trust · GBImperial College Healthcare NHS Trust · GBUniversity College London · GBGreat Ormond Street Hospital · GBSt. Mary's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report describes a case of juvenile myelomonocytic leukaemia (JMML) on a background of both perinatally acquired HIV infection and congenital cytomegalovirus, and management of antiretroviral therapy during haematopoietic stem cell transplant. Peripheral blood HIV viral load remained below the lower limit of detection throughout and following transplant and is currently <20 RNA copies/mL. The child is currently in remission from JMML, but HIV DNA remains detectable despite myeloablative conditioning and sustained plasma HIV viral suppression.

Identifiers

PMID31700667
PMCPMC6816122
OpenAlexW2997776333

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.