Evidence map›Paper›PMID 31700661›Full record

ArticleJournal of virus eradication2019

What is the effect of self-identified HIV activism in willingness to participate in HIV cure-related clinical trials? Results from the ANRS-APSEC study.

Marion Fiorentino, Christel Protière, Luis Sagaon-Teyssier, Mohamed Mimi, Lisa Fressard, Michael P Arnold, Olivier Lambotte, Janine Barbot, Sylvie Fainzang, Laurence Meyer and 4 more

Open access · goldAbstract readEditorial
In one paragraph

Article in Journal of virus eradication, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Marion FiorentinoAix Marseille University, INSERM, IRD, SESSTIM, Economic and Social Health Sciences and Medical Information Processing, Marseille, France.
Christel ProtièreAix Marseille University, INSERM, IRD, SESSTIM, Economic and Social Health Sciences and Medical Information Processing, Marseille, France.
Luis Sagaon-TeyssierAix Marseille University, INSERM, IRD, SESSTIM, Economic and Social Health Sciences and Medical Information Processing, Marseille, France.
Mohamed MimiAix Marseille University, INSERM, IRD, SESSTIM, Economic and Social Health Sciences and Medical Information Processing, Marseille, France.
Lisa FressardAix Marseille University, INSERM, IRD, SESSTIM, Economic and Social Health Sciences and Medical Information Processing, Marseille, France.
Michael P ArnoldInforming Change, Berkeley, USA.
Olivier LambotteINSERM, U1184, Université Paris-Sud , Hôpital de Bicêtre, Service de Médecine Interne, Le Kremlin-Bicêtre, France.
Janine BarbotINSERM, Centre d'étude des mouvements sociaux, Paris, France.
Sylvie FainzangCentre for Research in Medicine, Science, Health, Mental Health, and Society, Villejuif, France.
Laurence MeyerINSERM, U1018, Université Paris-Sud, Hôpital de Bicêtre, Department of Epidemiology, Le Kremlin-Bicêtre, France.
Cécile GoujardINSERM, U1018, Université Paris-Sud, Hôpital de Bicêtre, Department of Epidemiology, Le Kremlin-Bicêtre, France.
Marie PréauGRePS Lyon 2 Université, Bron, France.
Bruno SpireAix Marseille University, INSERM, IRD, SESSTIM, Economic and Social Health Sciences and Medical Information Processing, Marseille, France.
Marie Suzan-MontiAix Marseille University, INSERM, IRD, SESSTIM, Economic and Social Health Sciences and Medical Information Processing, Marseille, France.
Aix-Marseille Université · FREconomic & Social Sciences, Health Systems & Medical Informatics · FRInserm · FRBicêtre Hospital · FRCentre de Recherche Médecine, Sciences, Santé, Santé Mentale, Société · FRGroupe de Recherche en Psychologie Sociale · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEnrolling people living with HIV with undetectable viral load into HIV cure-related clinical trials (HCRCT) is challenging. Few data are currently available about the individual factors that influence willingness to participate in HCRCT (WPHCRCT). We hypothesised that WPHCRCT would be more frequent among people living with HIV considering themselves HIV activists. The objective of this study was to investigate the individual characteristics associated with both WPHCRCT and self-identification as an HIV activist.

methodsThe study enrolled 195 long-term ART-treated and virologically suppressed people living with HIV, followed-up in 19 French HIV services, 2016-2017. A Bayesian model averaging approach was used to assess correlates of both outcomes i.e. WPHCRCT and self-identified HIV activism.

resultsWPHCRCT was reported by 43% of participants and was positively associated with self-identification as an HIV activist (adjusted odds ratio [aOR] 2.90 95% confidence interval [CI] 2.17-3.63],

conclusionsWPHCRCT is strongly related to HIV activism, and also to positive psychosocial characteristics as a person living with HIV, especially regarding relationships with others. The desire to contribute to the fight against HIV for the sake of the HIV community and society should be taken into account to improve participation in upcoming HCRCT.

Indexed as

activismcure researchcure trialFranceHIVwillingness to participate in clinical trials

Identifiers

PMID31700661
PMCPMC6816119
OpenAlexW3004964907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.