Evidence map›Paper›PMID 31700653›Full record

ArticleNPJ biofilms and microbiomes

Reprioritization of biofilm metabolism is associated with nutrient adaptation and long-term survival of

Alistair Harrison, Rachael L Hardison, Rachel M Wallace, James Fitch, Derek R Heimlich, Meghan O' Bryan, Laura Dubois, Lisa St John-Williams, Robert P Sebra, Peter White and 4 more

Open access · goldAbstract read
In one paragraph

Article in NPJ biofilms and microbiomes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in cellular and infection microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Microbiology spectrum · 2023
    Article
  8. Article
  9. Review
  10. Non-typeableFrontiers in cellular and infection microbiology · 2023
    Article
  11. Article
  12. The Role ofFoods (Basel, Switzerland) · 2022
    Article
  13. Article
  14. Article
  15. Learning from -omics strategies applied to uncoverComputational and structural biotechnology journal · 2021
    Review
  16. Review
  17. Metabolic Shift of an Isogenic Strain ofInternational journal of molecular sciences · 2020
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Alistair Harrison1The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, 700 Children's Drive, Columbus, OH 43205 USA.ORCID 0000-0002-5741-7312
Rachael L Hardison1The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, 700 Children's Drive, Columbus, OH 43205 USA.ORCID 0000-0003-4624-1347
Rachel M Wallace1The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, 700 Children's Drive, Columbus, OH 43205 USA.
James FitchThe Abigail Wexner Research Institute at Nationwide Children's Hospital, The Steve and Cindy Rasmussen Institute for Genomic Medicine, 575 Children's Crossroad, Columbus, OH 43215 USA.
Derek R Heimlich1The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, 700 Children's Drive, Columbus, OH 43205 USA.
Meghan O' Bryan1The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, 700 Children's Drive, Columbus, OH 43205 USA.
Laura Dubois3Duke Proteomics and Metabolomics Core Facility, Duke Center for Genomic and Computational Biology, Duke University, 701 West Main Street, Durham, NC 27701 USA.
Lisa St John-Williams3Duke Proteomics and Metabolomics Core Facility, Duke Center for Genomic and Computational Biology, Duke University, 701 West Main Street, Durham, NC 27701 USA.
Robert P Sebra4Icahn School of Medicine at Mount Sinai, Icahn Institute and Department of Genetics & Genomic Sciences, 1 Gustave L. Levy Place, New York, NY 10029 USA.
Peter WhiteThe Abigail Wexner Research Institute at Nationwide Children's Hospital, The Steve and Cindy Rasmussen Institute for Genomic Medicine, 575 Children's Crossroad, Columbus, OH 43215 USA.ORCID 0000-0002-5218-5903
M Arthur Moseley3Duke Proteomics and Metabolomics Core Facility, Duke Center for Genomic and Computational Biology, Duke University, 701 West Main Street, Durham, NC 27701 USA.
J Will Thompson3Duke Proteomics and Metabolomics Core Facility, Duke Center for Genomic and Computational Biology, Duke University, 701 West Main Street, Durham, NC 27701 USA.
Sheryl S Justice1The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, 700 Children's Drive, Columbus, OH 43205 USA.ORCID 0000-0002-7059-3759
Kevin M Mason1The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, 700 Children's Drive, Columbus, OH 43205 USA.ORCID 0000-0003-1975-5158
Nationwide Children's Hospital · USDuke University · USIcahn School of Medicine at Mount Sinai · US

Funding

A novel multifunctional role of diverse substrate binding and import by the Haemophilus Sap transporterR01AI139519 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI MASON, KEVIN M · 2019 to 2023
$2.3M
Disease severity of otitis media: Biofilms, invasion, and host responsesR01DC013313 · NIDCD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI JUSTICE, SHERYL S, MASON, KEVIN M · 2014 to 2018
$1.9M
Tryptophan metabolism in Haemophilus persistence and formation of intracellular communitiesR21AI164077 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI MASON, KEVIN M · 2021 to 2022
$424k
NIAID NIH HHS R01 AI139519NIAID NIH HHS R21 AI164077NIDCD NIH HHS R01 DC013313
6 · The paper itself

Abstract

Nontypeable

Indexed as

Adaptation, PhysiologicalMicrobial ViabilityBiofilmsGene Expression ProfilingHaemophilus influenzaeHemeIronMetabolismMetabolomeProteomeHemeIronProteomeBacteriologyBiofilms

Identifiers

PMID31700653
PMCPMC6831627
OpenAlexW2986710453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.