Evidence map›Paper›PMID 31700635›Full record

ArticleUnited European gastroenterology journal2019

Over-the-scope clips are cost-effective in recurrent peptic ulcer bleeding.

Armin Kuellmer, Juliane Behn, Benjamin Meier, Andreas Wannhoff, Dominik Bettinger, Robert Thimme, Karel Caca, Arthur Schmidt

Abstract read
In one paragraph

Article in United European gastroenterology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Advancing hemostasis: A meta-analysis of novelWorld journal of gastrointestinal endoscopy · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Armin KuellmerDepartment of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Juliane BehnDepartment of Gastroenterology and Oncology, Klinikum Ludwigsburg, Ludwigsburg, Germany.
Benjamin MeierDepartment of Gastroenterology and Oncology, Klinikum Ludwigsburg, Ludwigsburg, Germany.
Andreas WannhoffDepartment of Gastroenterology and Oncology, Klinikum Ludwigsburg, Ludwigsburg, Germany.
Dominik BettingerDepartment of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-8782-8729
Robert ThimmeDepartment of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Karel CacaDepartment of Gastroenterology and Oncology, Klinikum Ludwigsburg, Ludwigsburg, Germany.
Arthur SchmidtDepartment of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A recent prospective randomised controlled trial ('STING') showed superiority of over-the-scope clips compared to standard treatment in recurrent peptic ulcer bleeding. Cost-effectiveness studies on haemostasis with over-the-scope clips have not been reported so far. Objective: The aim of this study was to investigate whether the higher efficacy of the over-the-scope clips treatment outweighs the higher costs of the device compared to standard clips. Methods: For the analysis, the study population of the STING trial was used. Costs for the hospital stay in total as well as treatment-related costs were obtained. The average cost-effectiveness ratio, representing the mean costs per designated outcome, and the incremental cost-effectiveness ratio, expressing the additional costs of a new treatment strategy per difference in outcome were calculated. The designated outcome was defined as successful haemostasis without rebleeding within seven days, which was the primary endpoint of the STING trial. Average cost-effectiveness ratio and incremental cost-effectiveness ratio were calculated for total costs of the hospital stay as well as the haemostasis treatment alone. The cost-effectiveness analysis is taken from the perspective of the care provider. Conclusions: Over-the-scope clip treatment is cost-effective in recurrent peptic ulcer bleeding.

Indexed as

Surgical InstrumentsCost-Benefit AnalysisEndoscopy, Digestive SystemFibrin Tissue AdhesiveHemostasis, EndoscopicHemostaticsHumansPeptic Ulcer HemorrhageRecurrenceFibrin Tissue AdhesiveHemostaticsaverage cost-effectiveness ratiocost-effectiveness analysisincremental cost-effectiveness ratioOver-the-scope clipspeptic ulcer bleeding

Identifiers

PMID31700635
PMCPMC6826528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.