Evidence map›Paper›PMID 31700595›Full record

ReviewTherapeutic advances in chronic disease2019

Current approach to the diagnosis of atherosclerotic coronary artery disease: more questions than answers.

Adam J Nelson, Maddalena Ardissino, Peter J Psaltis

Registry-linked trialAbstract readReview
In one paragraph

Review in Therapeutic advances in chronic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06552663 (The Diagnostic Power Of Coronary Ct Angiography In Patients With Chest Pain And Zero Calcium Score), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06552663 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

The Diagnostic Power Of Coronary Ct Angiography In Patients With Chest Pain And Zero Calcium Score

Typeobservational_patient_registrySponsorAssiut UniversityRan2024 to 2025Enrolled75ConditionsCT - Coronary ThrombosisArmsCCTA
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  17. Medical Fuzzy-Expert System for Assessment of the Degree of Anatomical Lesion of Coronary Arteries.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adam J NelsonDuke Clinical Research Institute, Durham, NC, USA.
Maddalena ArdissinoDuke Clinical Research Institute, Durham, NC, USA.
Peter J PsaltisSouth Australian Health and Medical Research Institute, North Terrace, Adelaide, SA 5005, Australia.ORCID https://orcid.org/0000-0003-0222-5468

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite its commonality in routine clinical practice, the approach to a diagnosis of atherosclerotic coronary artery disease remains complex and, in part, contentious. The traditional dogma linking ischaemia to hard clinical outcomes has been questioned and reframed over the years; rather than being a predictor of hard clinical outcomes, the degree of ischaemia may simply be a marker of atherosclerotic disease burden. A renewed interest in the imaging of plaque burden has spawned the contemporary role of CT imaging for not only diagnosis and prognosis, but also for dictating downstream management. As the technology develops and evidence expands, decisions on investigative modalities remain centred around patient factors, local availability, test performance and cost. This review summarizes the available methods for diagnosis in the symptomatic patient and provides an overview of the current evidence behind functional and anatomical approaches.

Indexed as

coronary angiographycoronary artery diseasecoronary CT angiographymyocardial ischaemiastress testing

Identifiers

PMID31700595
PMCPMC6826912

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.