ReviewTherapeutic advances in gastroenterology2019
Linked color imaging for the detection of early gastrointestinal neoplasms.
Review in Therapeutic advances in gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Linked color imaging versus conventional white-light colonoscopy for the detection of colorectal polyps.The Cochrane database of systematic reviews · 2025Pooled it
- Efficacy of image-enhanced endoscopy for colorectal polyp detection.Clinical endoscopy · 2026Review
- Diagnostic value of linked color imaging for detecting gastritis subtypes and precancerous lesions.American journal of translational research · 2026Article
- The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysis.Clinical endoscopy · 2025Article
- Impact of narrow band imaging in prediction of histology of advanced colorectal neoplasia.Scientific reports · 2025Article
- Linked color imaging for the detection and treatment of serrated colon neoplasia: current status and future perspective.Therapeutic advances in gastroenterology · 2025Review
- Artificial intelligence in advanced endoscopic imaging: transforming optical diagnosis in gastroenterology.Frontiers in medicine · 2025Review
- Esophageal cancers missed at upper endoscopy in Central Norway 2004 to 2021 - A population-based study.BMC gastroenterology · 2024Article
- Global progress and future prospects of early gastric cancer screening.Journal of Cancer · 2024Review
- Histopathological features of glandular atrophy of the lamina propria of the gastric mucosa during its occurrence and development.BMC gastroenterology · 2023Article
- Advanced Imaging in Gastrointestinal Endoscopy: A Literature Review of the Current State of the Art.GE Portuguese journal of gastroenterology · 2023Review
- Impact of linked color imaging and blue laser imaging on the diagnosis of esophageal squamous cell carcinoma in iodine unstained areas.The Kaohsiung journal of medical sciences · 2023Article
- Article
- Clinical Usefulness of Linked Color Imaging for Detection and Characterization of UndifferentiatedType Early Gastric Cancer.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Linked Color Imaging for Stomach.Diagnostics (Basel, Switzerland) · 2023Review
- Current status and future perspective of linked color imaging for gastric cancer screening: a literature review.Journal of gastroenterology · 2023Review
- Mucosal imaging in colon polyps: New advances and what the future may hold.World journal of gastroenterology · 2022Review
- Endoscopic Diagnosis of Eosinophilic Esophagitis: Basics and Recent Advances.Diagnostics (Basel, Switzerland) · 2022Review
- The effect of proton pump inhibitors and vonoprazan on the development of 'gastric mucosal redness'.Biomedical reports · 2022Article
- Unsedated Transnasal Endoscopy: A Safe, Well-Tolerated and Accurate Alternative to Standard Diagnostic Peroral Endoscopy.Digestive diseases and sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In routine upper and lower gastrointestinal endoscopy, overlooking neoplastic lesions is inevitable even for well-trained endoscopists. Various methods have been reported to improve the detection of gastrointestinal neoplasms including chromoendoscopy, special endoscopes, and processor and image enhanced technologies. Equipment-based image enhanced endoscopy (e-IEE) using narrow band imaging (NBI) and blue laser imaging (BLI) is useful to characterize known lesions with magnification at a close-up view. However, they are not useful for the early detection of superficial, pale neoplasms, or both because of the weak image at a distant view in a wide lumen such as the stomach or colon. Linked color imaging (LCI) is a novel pre- and post-processing technology developed by Fujifilm Corporation that has sufficient brightness to illuminate a wide lumen. LCI delineates early gastric cancers as orange-red and intestinal metaplasia as purple. LCI improves the adenoma detection rate in the colon and decreases the polyp miss rate. LCI contributes to the detection of superficial lesions throughout the gastrointestinal tract by enhancing the color contrast between the neoplasm and the surrounding mucosa. LCI can distinguish them by their specific color allocation based mainly on the distribution of capillaries. The authors believe that moving forward, LCI should be used in routine upper and lower gastrointestinal endoscopy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.