Evidence map›Paper›PMID 31700510›Full record

ArticleTransfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie2019

Hematopoietic Chimera in a Male Blood Donor and His Dizygotic Twin Sister.

Marcos P Miola, Alessandro G Lopes, Alessandra P Silva, Edney G C Gomes, Leticia A F Machado, Wanessa A Veloso, Carlos A Costa, Roberta M Fachini, Octávio Ricci Junior, Cinara C Brandão de Mattos and 1 more

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In one paragraph

Article in Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marcos P MiolaDepartment of Molecular Biology, Medical School of São José do Rio Preto (FAMERP), São José do Rio Preto, Brazil.
Alessandro G LopesDepartment of Biology, Instituto de Biociências, Letras, Ciências Exatas (IBILCE), Campus de São José do Rio Preto, São José do Rio Preto, Brazil.
Alessandra P SilvaDepartment of Special Services, Hemotherapy Service, Marinha do Brasil, Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.
Edney G C GomesDepartment of Special Services, Hemotherapy Service, Marinha do Brasil, Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.
Leticia A F MachadoDepartment of Special Services, Hemotherapy Service, Marinha do Brasil, Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.
Wanessa A VelosoDepartment of Special Services, Hemotherapy Service, Marinha do Brasil, Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.
Carlos A CostaDepartment of Special Services, Hemotherapy Service, Marinha do Brasil, Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.
Roberta M FachiniDepartment of Medicine, Medical School of São Jose do Rio Preto (FAMERP), São José do Rio Preto, Brazil.
Octávio Ricci JuniorDepartment of Medicine, Medical School of São Jose do Rio Preto (FAMERP), São José do Rio Preto, Brazil.
Cinara C Brandão de MattosDepartment of Molecular Biology, Medical School of São José do Rio Preto (FAMERP), São José do Rio Preto, Brazil.
Luiz Carlos de MattosDepartment of Molecular Biology, Medical School of São José do Rio Preto (FAMERP), São José do Rio Preto, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twin hematopoietic chimera in humans is a phenomenon that was discovered accidentally and the prevalence of which remains unclear. The resolution of chimera cases requires studying family medical records, data analysis, and investigations of hematopoietic cells and cells from other tissues. The interactions among ABO, Lewis, and secretor histo-blood group systems are explored to resolve cases of hematopoietic chimera. Here we report a rare case of hematopoietic chimera where twins present a mixed field reaction in the ABO, Rh, and Kidd red blood cell phenotyping. Using red blood cells separated from the mixed field as well as molecular approaches and investigations of family members, we identify inconsistent genotypes with the Mendelian inheritance pattern when comparing the peripheral blood with the buccal epithelium of the male twin and his twin sister. Analysis of the ABO, Lewis, and secretor phenotypes, and genomic DNA from buccal epithelium showed the genotypes

Indexed as

Blood groupsChimerismDizygotic twinsMolecular analysisPhenotyping

Identifiers

PMID31700510
PMCPMC6739710

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.