Evidence map›Paper›PMID 31700242›Full record

ArticleAnnals of gastroenterology

The utility of early post-liver transplantation model for end-stage liver disease score in prediction of long-term mortality.

Habibollah Dashti, Amirpasha Ebrahimi, Niloofar Razavi Khorasani, Bobak Moazzami, Fatemeh Khojasteh, Sedighe Hosseini Shabanan, Ali Jafarian

Abstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Habibollah DashtiDepartment of General Surgery, School of Medicine, Tehran University of Medical Sciences (Halibollah Dashti, Amirpasha Ebrahimi, Ali Jafarian).
Amirpasha EbrahimiDepartment of General Surgery, School of Medicine, Tehran University of Medical Sciences (Halibollah Dashti, Amirpasha Ebrahimi, Ali Jafarian).
Niloofar Razavi KhorasaniLiver Transplantation Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences (Habibollah Dashti, Niloofar Razavi Khorasani, Bobak Moazzami, Ali Jafarian).
Bobak MoazzamiLiver Transplantation Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences (Habibollah Dashti, Niloofar Razavi Khorasani, Bobak Moazzami, Ali Jafarian).
Fatemeh KhojastehTehran University of Medical Sciences (Fatemeh Khojasteh, Sediqe Hosseini Shabanan), Iran.
Sedighe Hosseini ShabananTehran University of Medical Sciences (Fatemeh Khojasteh, Sediqe Hosseini Shabanan), Iran.
Ali JafarianDepartment of General Surgery, School of Medicine, Tehran University of Medical Sciences (Halibollah Dashti, Amirpasha Ebrahimi, Ali Jafarian).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about the prognostic ability of post-liver transplantation (LT) model for end-stage liver disease (MELD) score measurement in assessing long-term outcomes. The aim of the present study was to investigate this possible relationship.

methodsIn this retrospective cohort study, the medical records of LT recipients operated under a LT program were reviewed. The accuracy of post-operation MELD score for predicting mortality was evaluated based on receiver operating characteristic (ROC) curves. Univariate and Cox proportional hazard regression models were used to assess the risk factors associated with mortality.

resultsEight hundred twenty-six consecutive LT recipients were included in the study. The areas under the ROC curve on postoperative days (POD) 5 and 9 for predicting 1-year mortality were 0.712 (95% confidence interval [CI] 0.614-0.811) and 0.682 (95%CI 0.571-0.798), respectively. A cutoff point of 14.5 was obtained for MELD score on POD5 that significantly differentiated between survivors and non-survivors with a sensitivity of 69.8% (95%CI 50.7-83.1) and a specificity of 57.2% (95%CI 50.6-63.6). In the Cox multivariate analysis, factors including MELD score on POD5 (hazard ratio [HR] 1.83, 95%CI 1.07-3.12; P=0.026), pre-transplant MELD (HR 1.064, 95%CI 1.025-1.104; P=0.001) and operation duration (min) (HR 1.004, 95%CI 1.003-1.006; P=0.013) were identified as independent risk factors for predicting overall survival.

conclusionThe immediate postoperative MELD scores after LT may be of value in predicting mortality and could be used as a tool for postoperative risk assessment of patients.

Indexed as

cirrhosisLiver transplantationmodel for end-stage liver disease scoreoutcome

Identifiers

PMID31700242
PMCPMC6826064

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.