Evidence map›Paper›PMID 31700234›Full record

ArticleAnnals of gastroenterology

Venous thromboembolism prophylaxis in inflammatory bowel disease flare-ups.

Osama Kaddourah, Laith Numan, Sravan Jeepalyam, Omar Abughanimeh, Mouhanna Abu Ghanimeh, Khalil Abuamr

Open access · diamondAbstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Is extended venous thromboprophylaxis required in patients undergoing ileal pouch procedure for ulcerative colitis?Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Inflammatory Bowel Disease Therapy and Venous Thromboembolism.Current treatment options in gastroenterology · 2020
    Article
  17. Inflammatory Bowel Disease and Thrombosis: A National Inpatient Sample Study.TH open : companion journal to thrombosis and haemostasis · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Osama KaddourahDepartment of Gastroenterology (Osama Kaddourah, Khalil Abuamr).
Laith NumanInternal Medicine (Laith Numan, Sraven Jeepalyam, Omar Abughanimeh), University of Missouri-Kansas City, Missouri.
Sravan JeepalyamInternal Medicine (Laith Numan, Sraven Jeepalyam, Omar Abughanimeh), University of Missouri-Kansas City, Missouri.
Omar AbughanimehInternal Medicine (Laith Numan, Sraven Jeepalyam, Omar Abughanimeh), University of Missouri-Kansas City, Missouri.
Mouhanna Abu GhanimehGastroenterology, Henry Ford Health System, Detroit, Michigan (Mouhanna Abu Ghanimeh), USA.
Khalil AbuamrDepartment of Gastroenterology (Osama Kaddourah, Khalil Abuamr).
Khalifa University of Science and Technology · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel disease (IBD) is a set of chronic inflammatory diseases associated with significant morbidity. Generally, IBD patients have twice the risk of venous thromboembolism (VTE) compared to healthy controls. VTE in IBD is associated with greater morbidity and mortality. This is compounded by the underutilization of pharmacological anticoagulation in hospitalized patients with IBD. One study showed that half the IBD patients who developed VTE were not receiving any thrombotic prophylaxis.

methodWe carried out a retrospective chart review of VTE prophylaxis use and safety in patients admitted with IBD flare-up between 2014 and 2017.

resultsWe evaluated 233 patients (mean age 36.7 years; 53.6% male). Of these patients, 55.2% were Caucasian and 40.5% were African American; 72.5% had Crohn's disease and 21% ulcerative colitis. About one-third of our patients were on chronic steroids. Pharmacological prophylaxis was used in 39.7% of the patients. This significantly correlated with male sex, recent surgery, history of VTE, smoking, and chronic steroid use. Meanwhile, hematochezia, aspirin use, and a history of gastrointestinal bleeding were correlated with less use of pharmacological prophylaxis. Patients receiving pharmacological prophylaxis showed no difference in the incidence of bleeding events.

conclusionsMultiple factors were associated with the use of pharmacological prophylaxis in hospitalized patients, including sex, steroid use, history of VTE events or gastrointestinal bleeding, and hematochezia. The incidence of major bleeding was not significantly greater in IBD patients receiving pharmacological prophylaxis.

Indexed as

Inflammatory bowel diseasepreventionprophylaxisvenous thromboembolism

Identifiers

PMID31700234
PMCPMC6826077
OpenAlexW2972236476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.