ArticleAnnals of gastroenterology
Association between irritable bowel syndrome and asthma: a meta-analysis and systematic review.
Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Irritable Bowel Syndrome and Allergic Diseases: A Nationwide Study of 1.5 Million Adolescents.Digestive diseases and sciences · 2026Article
- Psychometric properties of the Arabic IMPACT Bowel Function Short Form for assessing pelvic floor dysfunctions symptoms.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026Article
- Association between asthma and juvenile idiopathic arthritis in children in the United States: a propensity score weighted cross-sectional study.Pediatric rheumatology online journal · 2026Article
- Searching for the Perfect Sleeve Gastrectomy: The Role of Preoperative pHmetry in the Incidence of Postoperative Reflux Disease.Obesity surgery · 2026Article
- An atlas of the shared genetic architecture between atopic and gastrointestinal diseases.Communications biology · 2024Article
- Dachengqi Decoction alleviates intestinal inflammation in ovalbumin-induced asthma by reducing group 2 innate lymphoid cells in a microbiota-dependent manner.Journal of traditional and complementary medicine · 2023Article
- Artificial intelligence processing electronic health records to identify commonalities and comorbidities cluster at Immuno Center Humanitas.Clinical and translational allergy · 2022Article
- Rome IV Criteria-Defined Irritable Bowel Syndrome in Atopic Patients and the Effect of Anxiety and Depression: A Case-Control Study.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022Article
- Asthma and the risk of gastrointestinal disorders: a Mendelian randomization study.BMC medicine · 2022Article
- Network Pharmacology and Molecular Docking Study of Yupingfeng Powder in the Treatment of Allergic Diseases.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Update on the Role of Allergy in Pediatric Functional Abdominal Pain Disorders: A Clinical Perspective.Nutrients · 2021Review
- Prevalence and Symptom Characteristics of Irritable Bowel Syndrome Among Bronchial Asthma Patients in Pakistan.Cureus · 2020Article
- Human Respiratory and Gut Microbiomes-Do They Really Contribute to Respiratory Health?Frontiers in pediatrics · 2020Review
- Prevalence of Subthreshold Depression Among Constipation-Predominant Irritable Bowel Syndrome Patients.Frontiers in psychology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder often seen in outpatient clinics. Diagnosing IBS is often challenging, as it frequently presents with other complicated rheumatological and psychiatric conditions. Asthma has often been associated with gastrointestinal conditions such as gastroesophageal reflux disease and eosinophilic esophagitis. This review and meta-analysis aimed at a better understanding of the association between the conditions.
methodsA comprehensive literature review was completed using MEDLINE and EMBASE databases through January 2019. Case-control, cross-sectional and cohort studies that evaluated the association between asthma and IBS were divided into 2 groups: the first included studies that identified patients with asthma first and then looked for the presence of IBS. The second group included studies that identified IBS patients first and then looked for the presence of asthma. Random effects meta-analysis was conducted using STATA 15.
resultsThe search strategy generated a total of 634 studies and 10 eligible studies (8 case-control and 2 cross-sectional) were selected for meta-analysis. Analysis showed that asthmatics have twice the risk of having IBS (pooled odds ratio [OR] 2.0, 95% confidence interval [CI] 1.5-2.8), and patients with IBS have twice the risk of having asthma (pooled OR 2.2, 95%CI 1.3-3.9).
conclusionsThis study highlights that the risk of asthma is considerably higher in IBS patients and vice versa. Physicians should look out for pulmonary symptoms in IBS patients and consider evaluation with spirometry when necessary. Likewise, asthmatics presenting with gastrointestinal symptoms may need consultation and evaluation for IBS.
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