ReviewAnnals of gastroenterology
Paradigm shift: the Copernican revolution in diverticular disease.
Review in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Does the microbiome play a role in the pathogenesis of colonic diverticular disease? A systematic review.Journal of gastroenterology and hepatology · 2023Pooled it
- Trial
- Outcome variation in the use and duration of antibiotic therapy in patients presenting with acute diverticulitis.BMC gastroenterology · 2025Article
- Description of the Distinctive Changes in the Colonic Microbiome Associated with Irritable Bowel Syndrome, Uncomplicated Diverticulitis, and Tubular Adenoma.Biomedicines · 2025Article
- Diverticular disease and risk of incident major adverse cardiovascular events: a nationwide matched cohort study.European heart journal. Quality of care & clinical outcomes · 2025Article
- Safety and efficacy of faecal microbiota transplantation in patients with acute uncomplicated diverticulitis: study protocol for a randomised placebo-controlled trial.Therapeutic advances in gastroenterology · 2025Article
- Recent updates on classification and unsolved issues of diverticular disease: a narrative review.Journal of Yeungnam medical science · 2024Article
- Rifaximin in diverticulosis and diverticular disease: a national survey among Italian gastroenterologists and general practitioners.Internal and emergency medicine · 2024Article
- Microbiota composition and mucosal immunity in patients with asymptomatic diverticulosis and controls.PloS one · 2021Article
- Diverticulosis and neoplastic lesions in screening colonoscopy: a large, multicenter study.Annals of gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diverticular disease (DD) is an umbrella definition that includes different clinical conditions ranging from diverticulosis to severe and potentially life-threatening complications. In the last decade, new concepts regarding pathogenetic alterations have been developed, while the diagnostic, clinical and therapeutic approaches to the management of DD patients have changed. The protective role of dietary factors (i.e., fiber) has been questioned, whilst some drugs widely used in clinical practice have been found to have a deleterious effect. The use of antibiotics in all patients with acute uncomplicated diverticulitis was reconsidered, as well as the need for a surgical approach in these patients. Conflicting recommendations in different guidelines were proposed for the treatment of symptomatic uncomplicated DD. An endoscopic classification of DD was introduced, and a "curative" endoscopic approach has been pioneered. Based on these observations, which together amount to a kind of "Copernican revolution" in the management of DD patients, we performed a comprehensive and critical reappraisal of the proposed modifications, aiming to discriminate between certainties and doubts on this issue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.