ReviewAnnals of gastroenterology
Diagnosis and management of acute esophageal necrosis.
Review in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Acute esophageal necrosis in patients with diabetic ketoacidosis: a systematic review of clinical features and outcomes.Clinical journal of gastroenterology · 2026Pooled it
- Markers of Prognosis for Acute Esophageal Necrosis: A Systematic Review.Digestive diseases (Basel, Switzerland) · 2025Pooled it
- Acute esophageal necrosis: serial endoscopic documentation of rapid mucosal restoration.Internal and emergency medicine · 2026Article
- Article
- Acute Esophageal Necrosis Secondary to Cardiogenic Shock: A Case Report and Review of the Literature.Cureus · 2026Article
- The two-hit hypothesis in acute esophageal necrosis: black esophagus in severe atherosclerosis and untreated gastroesophageal reflux disease: a case report.Journal of medical case reports · 2026Article
- Article
- Acute oesophageal necrosis: single centre experience.BMC gastroenterology · 2026Article
- Case report: Three contrasting presentations of acute oesophageal necrosis and the determinants of outcome.Frontiers in medicine · 2026Article
- Two Rare Complications. Acute Esophageal Necrosis Followed by an Active Bleeding Dieulafoy Lesion.ACG case reports journal · 2025Article
- Black Esophagus in a Critically Ill Patient With Septic Shock: A Case Report of a Rare Entity.Cureus · 2025Article
- Tacrolimus-Induced Acute Esophageal Necrosis Postorthotopic Liver Transplantation.ACG case reports journal · 2025Article
- A Remarkable Occurrence: Esophageal Necrosis Induced by Acute Coronary Syndromes - An Uncommon Encounter-Case Report.Acta Cardiologica Sinica · 2025Article
- Black Esophagus Under the Scope: Gurvits Syndrome in a Patient With Diabetic Ketoacidosis.Cureus · 2025Article
- Managing Acute Esophageal Necrosis Secondary to Diabetic Ketoacidosis in a Rural Centre: A Case Report and Proposed Algorithm for Management.Clinical case reports · 2025Article
- Multidisciplinary Management of Acute Esophageal Necrosis Secondary to Alcoholic Lactic Acidosis: A Case Report.Reports (MDPI) · 2025Article
- Article
- Pembrolizumab-Associated Acute Esophageal Necrosis: A Case Report and Literature Review.HCA healthcare journal of medicine · 2025Article
- Acute Esophageal Necrosis (Gurvits Syndrome): A Rare Cause of Upper Gastrointestinal Bleeding in Somalia.International medical case reports journal · 2025Article
- Multidisciplinary Management of a Patient with acute Oesophageal Necrosis and Severe Neurological Symptoms with Full Recovery.European journal of case reports in internal medicine · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute esophageal necrosis is a rare syndrome classically characterized by a striking endoscopic image of diffuse and circumferential black mucosal discoloration of distal esophagus, with an abrupt transition at the gastroesophageal junction and variable proximal extension. The typical patient is an older male with general debilitation and multiple comorbidities presenting with hematemesis or melena. The pathophysiology usually involves a combination of esophageal ischemia, backflow injury from gastric chemical contents and impaired mucosal reparative mechanisms associated with debilitated physical states. It may arise in the setting of hemodynamic compromise, diabetic ketoacidosis, hypothermia, alcoholic intoxication, trauma, inflammatory diseases, esophageal local infection, solid organ transplantation, postoperative status, drugs or acute gastric outlet obstruction, usually in the background of a chronic debilitating process, where the concurrent presence of multiple risk factors, including diabetes mellitus, hypertension, malnutrition, malignancy or alcohol abuse, places a patient at higher risk. The characteristic endoscopic appearance establishes the diagnosis. Biopsy is supportive but not required. Management is mainly supportive and consists of correcting coexisting conditions, fluid therapy, bowel rest, intravenous proton pump inhibitor therapy and red blood cell transfusion as needed. Although this is a serious life-threatening condition, appropriate treatment may result in a favorable outcome in the majority of patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.