Evidence map›Paper›PMID 31700189›Full record

ArticleNature medicine2019

Genomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients.

Idan Yelin, Kelly B Flett, Christina Merakou, Preeti Mehrotra, Jason Stam, Erik Snesrud, Mary Hinkle, Emil Lesho, Patrick McGann, Alexander J McAdam and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Nature medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 167 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed, 3 pooled it
31.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

167 citing papers in PubMed, 3 syntheses or guidelines pooled it, 288 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Probiotics for treating acute infectious diarrhoea.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Effects of Low-Energy Diets Supplemented withAnimals : an open access journal from MDPI · 2026
    Article
  19. Article
  20. Article

107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Idan Yelin *Department of Biology, Technion-Israel Institute of Technology, Haifa, Israel.ORCID http://orcid.org/0000-0003-2515-4113
Kelly B Flett *Division of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Christina Merakou *Harvard Medical School, Boston, MA, USA.
Preeti MehrotraDivision of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Jason StamWalter Reed Army Institute of Research, Silver Spring, MD, USA.
Erik SnesrudWalter Reed Army Institute of Research, Silver Spring, MD, USA.
Mary HinkleWalter Reed Army Institute of Research, Silver Spring, MD, USA.
Emil LeshoWalter Reed Army Institute of Research, Silver Spring, MD, USA.
Patrick McGannWalter Reed Army Institute of Research, Silver Spring, MD, USA.
Alexander J McAdamDivision of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Thomas J SandoraDivision of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA. thomas.sandora@childrens.harvard.edu.ORCID http://orcid.org/0000-0003-1755-5881
Roy KishonyDepartment of Biology, Technion-Israel Institute of Technology, Haifa, Israel. rkishony@technion.ac.il.ORCID http://orcid.org/0000-0002-5013-5072
Gregory P PriebeDivision of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA. gregory.priebe@childrens.harvard.edu.ORCID http://orcid.org/0000-0001-9831-0354
Boston Children's Hospital · USWalter Reed Army Institute of Research · USTechnion – Israel Institute of Technology · IL

Funding

The population genetics of antibiotic resistance in multi-drug environmentsR01GM081617 · NIGMS · TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY · PI KISHONY, ROY · 2007 to 2018
$3.7M
European Research Council 281891NIGMS NIH HHS R01 GM081617
6 · The paper itself

Abstract

Probiotics are routinely administered to hospitalized patients for many potential indications

Indexed as

BacteremiaDiarrheaDrug Resistance, BacterialGenetic VariationGenome, BacterialGenomicsHumansIntensive Care UnitsLactobacillusMutationPhylogenyPolymorphism, Single NucleotideProbioticsWhole Genome Sequencing

Identifiers

PMID31700189
PMCPMC6980696
OpenAlexW2987760949

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.