ArticleNature medicine2019
Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells.
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Article in Nature medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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59citing papers in PubMed
–field-weighted citation impact
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Who cites it
59 citing papers in PubMed.
- The making of cells and organs in xenogeneic animal bioreactor.Signal transduction and targeted therapy · 2026Review
- African pygmy mouse iPSCs as a model for in vitro embryogenesis, interspecies chimerism, and blastocyst complementation.Cell reports methods · 2026Article
- Mesendodermal cells fail to contribute to heart formation following blastocyst injection.Biochemistry and biophysics reports · 2025Article
- Generation of parathyroid glands from pluripotent stem cells.Endocrine journal · 2025Review
- Gastruloid patterning reflects division of labor among biased stem cell clones.bioRxiv : the preprint server for biology · 2025Article
- Blastocyst complementation: current progress and future directions in xenogeneic organogenesis.Stem cell research & therapy · 2025Review
- Review
- Blastocyst complementation-based rat-derived heart generation reveals cardiac anomaly barriers to interspecies chimera development.iScience · 2024Article
- Parathyroid Gland Generation from Pluripotent Stem Cells.Endocrinology and metabolism (Seoul, Korea) · 2024Review
- CRISPR-Cas9 Genome Editing Allows Generation of the Mouse Lung in a Rat.American journal of respiratory and critical care medicine · 2024Article
- Can a Rat Breathe through a Mouse's Lung?American journal of respiratory and critical care medicine · 2024Article
- Generation of salivary glands derived from pluripotent stem cells via conditional blastocyst complementation.Cell reports · 2024Article
- Generating an organ-deficient animal model using a multi-targeted CRISPR-Cas9 system.Scientific reports · 2024Article
- Article
- Generation of rat forebrain tissues in mice.Cell · 2024Article
- Lung repair and regeneration: Advanced models and insights into human disease.Cell stem cell · 2024Review
- Article
- Functional calcium-responsive parathyroid glands generated using single-step blastocyst complementation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- An immunostimulatory glycolipid that blocks SARS-CoV-2, RSV, and influenza infections in vivo.Nature communications · 2023Article
- Realizations of vascularized tissues: FromBiophysics reviews · 2023Review
Corrections and comments
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Authors and funding
14 authors.
Munemasa Mori *Columbia Center for Human Development and Division of Pulmonary, Allergy, Critical Care, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. mm4452@cumc.columbia.edu.ORCID http://orcid.org/0000-0002-7283-7198
Kazuhiro FuruhashiColumbia Center for Translational Immunology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Jennifer A DanielssonDepartment of Anethesiology, Columbia University Irving Medical Center, New York, NY, USA.
Yuichi HirataColumbia Center for Translational Immunology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Miwako KakiuchiColumbia Center for Translational Immunology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Chyuan-Sheng LinBernard and Shirlee Brown Glaucoma Laboratory, Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
Mayu OhtaColumbia Center for Human Development and Division of Pulmonary, Allergy, Critical Care, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Paul RiccioColumbia Center for Human Development and Division of Pulmonary, Allergy, Critical Care, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Yusuke TakahashiInstitute for Stem Cell Biology and Regenerative Medicine, Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Xinjing XuDepartment of Genetics and Development and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA.
Charles W EmalaDepartment of Anethesiology, Columbia University Irving Medical Center, New York, NY, USA.
Chao LuDepartment of Genetics and Development and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-0982-8122
Hiromitsu Nakauchi *Institute for Stem Cell Biology and Regenerative Medicine, Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. nakauchi@stanford.edu.ORCID http://orcid.org/0000-0002-9841-6973
Wellington V Cardoso *Columbia Center for Human Development and Division of Pulmonary, Allergy, Critical Care, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. wvc2104@cumc.columbia.edu.ORCID http://orcid.org/0000-0002-8868-9716
Funding
Mechanisms Controlling Expansion and Lineage Specification of Airway Progenitors in Development and DiseaseR35HL135834 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CARDOSO, WELLINGTON V. · 2017 to 2023
$6.7MRegulatory Mechanisms of Cell Competition in Lung RegenerationR01HL148223 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MORI, MUNEMASA · 2019 to 2022
$2.1MTargeting airway smooth muscle chloride fluxes for bronchorelaxationR01HL122340 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EMALA, CHARLES W · 2015 to 2018
$1.6MAntagonism of the Calcium -Activated Chloride Channel TMEM16A; Beneficial Therapeutic Effects on Airway Epithelium and Smooth MuscleK08HL132203 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DANIELSSON, JENNIFER ANN · 2017 to 2021
$821kBecton Dickinson LSR II Analytical Flow CytometerS10RR027050 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLYNES, RAPHAEL A. · 2011 to 2011
$413kNCRR NIH HHS S10 RR027050NHLBI NIH HHS K08 HL132203NHLBI NIH HHS R01 HL122340NHLBI NIH HHS R01 HL148223NHLBI NIH HHS R35 HL135834
Abstract
Millions of people worldwide with incurable end-stage lung disease die because of inadequate treatment options and limited availability of donor organs for lung transplantation
Indexed as
AcylationAnimalsbeta CateninBlastocystCell DifferentiationDisease Models, AnimalDNA MethylationHistonesHumansLungLung DiseasesMiceOrganogenesisPluripotent Stem CellsReceptor, Fibroblast Growth Factor, Type 2Regenerationbeta CateninCTNNB1 protein, mouseFgfr2 protein, mouseHistonesReceptor, Fibroblast Growth Factor, Type 2
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LicenceCC BY-NC
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.