ArticleNature medicine2019
Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans.
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Article in Nature medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers.
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109citing papers in PubMed
18.3field-weighted citation impact, top 1% of its field
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Who cites it
109 citing papers in PubMed, 175 citations in OpenAlex.
- Anthocyanins regulate serum adipsin and visfatin in patients with prediabetes or newly diagnosed diabetes: a randomized controlled trial.European journal of nutrition · 2021Trial
- Human β-Cell Dedifferentiation and Diabetes.Journal of diabetes · 2026Review
- Glucose-dependent regulation of hepatic adipsin controls glucose uptake and tolerance.Molecular medicine (Cambridge, Mass.) · 2026Article
- Sex-specific efficacy of curcumin-loaded nanoparticles and insulin for ocular-cardiac complications in type 2 diabetes mice.iScience · 2026Article
- Type 2 and type 1 diabetes have opposing effects on the systemic murine complement alternative pathway.iScience · 2026Article
- Myeloid-Derived Growth Factor Improves Endothelial Progenitor Cell Function and Angiogenesis in Mice With Diabetic Hindlimb Ischemia by Activating Akt/HIF-1α Signalling Pathway.Journal of cellular and molecular medicine · 2026Article
- Cell-type-specific proximity labeling of organ secretomes reveals energy balance-dependent proteomic remodeling.Cell reports · 2026Article
- Gestational diabetes as an inter-generational cardiometabolic risk factor: spotlight on emerging exerkines.Cardiovascular diabetology · 2026Review
- Helminth infection induces RELMα-dependent adipose tissue transcriptional reprogramming and protection against diet-induced obesity.bioRxiv : the preprint server for biology · 2026Article
- Circulating Adipsin as a Biomarker of Liver Fat Content in Prepubertal Children Born Small-for-Gestational-Age.International journal of molecular sciences · 2026Article
- DUSP family phosphatases in cell signaling, inflammation, and chronic diseases.Journal of biomedical science · 2026Review
- Zinc accumulation-induced integrated stress response triggers β-cell identity loss.Cell research · 2026Article
- Investigational treatments of β-cell failure and replacement.Diabetology international · 2026Review
- DUSP26 protects against acute kidney injury by dephosphorylating p53 at serine 312.Nature communications · 2026Article
- Radical footprinting in mammalian whole blood.Nature communications · 2026Article
- Cell type-specific proximity labeling of organ secretomes reveals energy balance-dependent proteomic remodeling.bioRxiv : the preprint server for biology · 2026Article
- Effects of crowberry (Food & nutrition research · 2026Article
- Adipocytokines as Pathogenic Mediators and Therapeutic Targets in Metabolic Syndrome-Related Cardiocerebrovascular Events.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Review
- How Adipocytes Orchestrate Inflammation Within Adipose Tissue?Biomolecules · 2025Review
- Identification and validation of biomarkers related to mitochondria-associated endoplasmic reticulum membranes in type 2 diabetes mellitus using peripheral blood transcriptomics.European journal of medical research · 2025Article
49 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 6 institutions in 1 country.
Nicolás Gómez-BanoyWeill Center for Metabolic Health and Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-3552-1768
J Sawalla GusehCorrigan Minehan Heart Center, Cardiovascular Research Center and Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0992-5635
Ge LiDepartment of Biochemistry, Weill Cornell Medicine, New York, NY, USA.
Alfonso Rubio-NavarroWeill Center for Metabolic Health and Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-5677-3123
Tong ChenWeill Center for Metabolic Health and Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
BreAnne PoirierWeill Center for Metabolic Health and Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Gregory PutzelJill Roberts Institute for Research in Inflammatory Bowel Disease, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Carolina RosselotDiabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Maria A PabónWeill Center for Metabolic Health and Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
João Paulo CamporezDepartments of Internal Medicine and Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.
Vijeta BhambhaniCorrigan Minehan Heart Center, Cardiovascular Research Center and Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Shih-Jen HwangPopulation Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Chen YaoPopulation Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-3944-7788
Rachel J PerryDepartments of Internal Medicine and Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.
Sushmita MukherjeeDepartment of Biochemistry, Weill Cornell Medicine, New York, NY, USA.
Martin G LarsonFramingham Heart Study, Framingham, MA, USA.
Daniel LevyPopulation Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Lukas E DowSandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Gerald I ShulmanDepartments of Internal Medicine and Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-1529-5668
Noah DephoureSandra and Edward Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Adolfo Garcia-OcanaDiabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mingming HaoDepartment of Biochemistry, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0003-4677-5111
Bruce M SpiegelmanDana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
Jennifer E HoCorrigan Minehan Heart Center, Cardiovascular Research Center and Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. jho1@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-7987-4768
James C LoWeill Center for Metabolic Health and Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA. jlo@med.cornell.edu.ORCID http://orcid.org/0000-0003-0244-1670
Cornell University · USHarvard University · USNational Institutes of Health · USYale University · USIcahn School of Medicine at Mount Sinai · USBoston University · US
Funding
Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold, GERALD I SHULMAN · 1993 to 2026
$44.0MStable Isotope and Metabolomics CoreP60DK020541 · NIDDK · YESHIVA UNIVERSITY · PI PESSIN, JEFFREY E. · 1986 to 2014
$29.8MTranslational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DONALD K. SCOTT · 2015 to 2026
$27.7MMULTIDISCIPLINARY RESEARCH TRAINING IN CARDIOLOGYT32HL007208 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Patrick Thomas Ellinor, David E Sosnovik · 1985 to 2026
$16.1MYale Mouse Metabolic Phenotyping CenterU24DK059635 · NIDDK · YALE UNIVERSITY · PI SHULMAN, GERALD I · 2001 to 2015
$8.9MEicosanoid Profiles as Determinants of HFpEFR01HL140224 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HO, JENNIFER E · 2018 to 2021
$3.1MThe Association of Metabolic Disease and Pulmonary HypertensionR01HL134893 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HO, JENNIFER E · 2017 to 2021
$2.9MDusp26 regulation of beta cell homeostasisR01DK121140 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI James C Lo · 2020 to 2026
$2.7MMicrobiome origins and insulin regulatory responses of the short chain fatty acid acetateR01DK114793 · NIDDK · YALE UNIVERSITY · PI GOODMAN, ANDREW L, SHULMAN, GERALD I · 2018 to 2021
$2.4MAn Obesity-Induced Kinase that Regulates Adipose Homeostasis and Metabolic DiseasesR01DK121844 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI LO, JAMES C · 2019 to 2023
$2.1MGlucagon Regulation of Hepatic Mitochondrial Activity and Glucose Metabolism by InsP3R-1R01DK116774 · NIDDK · YALE UNIVERSITY · PI SHULMAN, GERALD I · 2018 to 2021
$1.7MRegulation of adipose inflammation and metabolic syndrome by adipsin/factor DK08DK097303 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI LO, JAMES C · 2012 to 2016
$784kNHLBI NIH HHS N01 HC025195NHLBI NIH HHS R01 HL134893NHLBI NIH HHS R01 HL140224NHLBI NIH HHS T32 HL007208NIDDK NIH HHS K08 DK097303NIDDK NIH HHS P30 DK020541NIDDK NIH HHS P30 DK045735NIDDK NIH HHS P60 DK020541NIDDK NIH HHS R01 DK114793NIDDK NIH HHS R01 DK116774NIDDK NIH HHS R01 DK121140NIDDK NIH HHS R01 DK121844NIDDK NIH HHS R03 DK111762NIDDK NIH HHS U24 DK059635
Abstract
Type 2 diabetes is characterized by insulin resistance and a gradual loss of pancreatic beta cell mass and function
Indexed as
AnimalsBody Mass IndexCell DedifferentiationComplement C3aComplement Factor DDiabetes Mellitus, Type 2Dual-Specificity PhosphatasesGlucoseHumansHyperglycemiaInsulinInsulin ResistanceInsulin-Secreting CellsMiceMice, Inbred NODMitogen-Activated Protein Kinase PhosphatasesComplement C3aComplement Factor DDual-Specificity PhosphatasesDUSP26 protein, humanGlucoseInsulinMitogen-Activated Protein Kinase Phosphatases
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.