Evidence map›Paper›PMID 31700125›Full record

ArticleScientific reports2019

An aptasensor for the detection of Mycobacterium tuberculosis secreted immunogenic protein MPT64 in clinical samples towards tuberculosis detection.

Marzhan Sypabekova, Kanat Dukenbayev, Anna Tsepke, Akmaral Akisheva, Nurlan Oralbayev, Damira Kanayeva

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Simultaneous and sensitive detection ofFrontiers in bioengineering and biotechnology · 2025
    Article
  6. Article
  7. The application of aptamer in tuberculosis diagnosis: a systematic review.Tropical diseases, travel medicine and vaccines · 2024
    Review
  8. Review
  9. Article
  10. Aptamer-Based Technologies for Parasite Detection.Sensors (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Rapid diagnosis of TB using Aptamer-based assays forLung India : official organ of Indian Chest Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marzhan SypabekovaGraduate Program in Science, Engineering, and Technology, Nazarbayev University, Nur-Sultan, 010000, Kazakhstan.
Kanat DukenbayevDepartment of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, Nur-Sultan, 010000, Kazakhstan.ORCID http://orcid.org/0000-0002-6261-3908
Anna TsepkeAstana Antituberculosis Dispensary, Nur-Sultan, Kazakhstan.
Akmaral AkishevaAstana Antituberculosis Dispensary, Nur-Sultan, Kazakhstan.
Nurlan OralbayevAstana Antituberculosis Dispensary, Nur-Sultan, Kazakhstan.
Damira KanayevaDepartment of Biology, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan, 010000, Kazakhstan. dkanayeva@nu.edu.kz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work presents experimental results on detection of Mycobacterium tuberculosis secreted protein MPT64 using an interdigitated electrode (IDE) which acts as a platform for capturing an immunogenic protein and an electrochemical impedance spectroscopy (EIS) as a detection technique. The assay involves a special receptor, single stranded DNA (ssDNA) aptamer, which specifically recognizes MPT64 protein. The ssDNA immobilization on IDE was based on a co-adsorbent immobilization at an optimized ratio of a 1/100 HS-(CH

Indexed as

Biosensing TechniquesAntigens, BacterialAptamers, NucleotideMicroscopy, Atomic ForceMycobacterium tuberculosisROC CurveSELEX Aptamer TechniqueSensitivity and SpecificityTuberculosisAntigens, BacterialAptamers, NucleotideMPT64 protein, Mycobacterium tuberculosis

Identifiers

PMID31700125
PMCPMC6838340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.