Evidence map›Paper›PMID 31700095›Full record

Trial reportScientific reports2019

Functional neuroanatomy of interoceptive processing in children and adolescents: a pilot study.

M Klabunde, H Juszczak, T Jordan, J M Baker, J Bruno, V Carrion, A L Reiss

Abstract readClinical TrialComparative Study
In one paragraph

Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M KlabundeCentre for Brain Sciences, Department of Psychology, University of Essex, Wivenhoe Park, United Kingdom. mklabunde@essex.au.uk.ORCID http://orcid.org/0000-0003-4210-7968
H JuszczakUniversity of California, San Francisco Medical Center, San Francisco, USA.
T JordanCenter for Interdisciplinary Brain Sciences Research, Division of Interdisciplinary Brain Sciences, Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford University, Stanford, USA.
J M BakerCenter for Interdisciplinary Brain Sciences Research, Division of Interdisciplinary Brain Sciences, Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford University, Stanford, USA.ORCID http://orcid.org/0000-0001-7295-6122
J BrunoCenter for Interdisciplinary Brain Sciences Research, Division of Interdisciplinary Brain Sciences, Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford University, Stanford, USA.ORCID http://orcid.org/0000-0001-7705-2456
V CarrionDivision of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford University, Stanford, USA.
A L ReissCenter for Interdisciplinary Brain Sciences Research, Division of Interdisciplinary Brain Sciences, Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford University, Stanford, USA.

Funding

TRAINING FOR CHILD PSYCHIATRY AND CHILD DEVELOPMENTT32MH019908 · NIMH · STANFORD UNIVERSITY · PI IAN H GOTLIB, DAVID S HONG · 1993 to 2026
$6.3M
NIMH NIH HHS T32 MH019908
6 · The paper itself

Abstract

In adults, interoception - the sense of the physiological condition of the body - appears to influence emotion processing, cognition, behavior and various somatic and mental health disorders. Adults demonstrate frontal-insula-parietal-anterior cingulate cortex activation during the heartbeat detection task, a common interoceptive measure. Little, however, is known about the functional neuroanatomy underlying interoception in children. The current pilot study examined interoceptive processing in children and adolescents with fMRI while using the heartbeat detection task. Our main findings demonstrate that children as young as the age of six activate the left insula, cuneus, inferior parietal lobule and prefrontal regions. These findings are similar to those in adults when comparing heartbeat and tone detection conditions. Age was associated with increased activation within the dACC, orbital frontal cortex and the mid-inferior frontal gyri. Thus, our pilot study may provide important information about the neurodevelopment of interoceptive processing abilities in children and a task for future interoception neuroimaging studies in children.

Indexed as

Magnetic Resonance ImagingAdolescentAdultBrain MappingCerebral CortexChildFemaleHumansInteroceptionMalePilot Projects

Identifiers

PMID31700095
PMCPMC6838093

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.