Evidence map›Paper›PMID 31700067›Full record

ArticleScientific reports2019

LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells.

Wenchuan Qi, Zhenhua Li, Longjiang Xia, Jiangshan Dai, Qiao Zhang, Chuanfang Wu, Si Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers.

0numbers the graph read from it
0cells of the map it votes in
153citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

153 citing papers in PubMed, 225 citations in OpenAlex.

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93 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Wenchuan QiKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610065, Chengdu, Sichuan, P.R. China.
Zhenhua LiAffiliated Hospital of Changchun University of Traditional Chinese Medicine, 130117, Changchun, Jilin, P.R. China.
Longjiang XiaChengdu University of Traditional Chinese Medicine, 611130, Chengdu, Sichuan, P.R. China.
Jiangshan DaiKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610065, Chengdu, Sichuan, P.R. China.
Qiao ZhangChina-Japan Union Hospital of Jilin University, 130033, Changchun, Jilin, P.R. China.
Chuanfang WuKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610065, Chengdu, Sichuan, P.R. China.
Si XuKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610065, Chengdu, Sichuan, P.R. China. bearpp@126.com.
Sichuan University · CNChangchun University · CNChengdu University of Traditional Chinese Medicine · CNJilin University · CNSichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is a non-apoptotic, iron-dependent oxidative form of cell death that is specifically induced by erastin in RAS mutant cancer cells. Ferroptotic cell death is the result of membrane lipid peroxide damage caused by the accumulation of hydroxyl radicals derived from H

Indexed as

Carcinoma, HepatocellularFerroptosisGA-Binding Protein Transcription FactorHep G2 CellsHumansLiver NeoplasmsNeoplasm ProteinsOxidative StressPeroxiredoxinsPiperazinesRNA, Long NoncodingRNA, NeoplasmerastinGA-Binding Protein Transcription FactorGABPB1 protein, humanNeoplasm ProteinsPeroxiredoxinsPiperazinesPRDX5 protein, humanRNA, Long NoncodingRNA, Neoplasm

Identifiers

PMID31700067
PMCPMC6838315
OpenAlexW2984537832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.