Evidence map›Paper›PMID 31700036›Full record

ArticleScientific reports2019

Direct, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit α

Ehab El-Awaad, Galyna Pryymachuk, Cora Fried, Jan Matthes, Jörg Isensee, Tim Hucho, Wolfram F Neiss, Mats Paulsson, Stefan Herzig, Frank Zaucke and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Pathophysiological Roles of Auxiliary Calcium Channel αHandbook of experimental pharmacology · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Ehab El-AwaadInstitute II for Pharmacology, Centre of Pharmacology, Medical Faculty, University of Cologne, Gleueler Str. 24, D-50931, Cologne, Germany.
Galyna PryymachukDepartment of Anatomy I, Medical Faculty, University of Cologne, Kerpener Str. 62, D-50937, Cologne, Germany.
Cora FriedInstitute II for Pharmacology, Centre of Pharmacology, Medical Faculty, University of Cologne, Gleueler Str. 24, D-50931, Cologne, Germany.
Jan MatthesInstitute II for Pharmacology, Centre of Pharmacology, Medical Faculty, University of Cologne, Gleueler Str. 24, D-50931, Cologne, Germany.
Jörg IsenseeExperimental Anaesthesiology and Pain Research, Department of Anaesthesiology and Intensive Care Medicine, Medical Faculty, University of Cologne, Robert-Koch-Str. 10, D-50931, Cologne, Germany.ORCID http://orcid.org/0000-0002-3390-0051
Tim HuchoExperimental Anaesthesiology and Pain Research, Department of Anaesthesiology and Intensive Care Medicine, Medical Faculty, University of Cologne, Robert-Koch-Str. 10, D-50931, Cologne, Germany.ORCID http://orcid.org/0000-0002-4147-9308
Wolfram F NeissDepartment of Anatomy I, Medical Faculty, University of Cologne, Kerpener Str. 62, D-50937, Cologne, Germany.
Mats PaulssonInstitute for Biochemistry II, Centre for Biochemistry, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, D-50931, Cologne, Germany.
Stefan HerzigInstitute II for Pharmacology, Centre of Pharmacology, Medical Faculty, University of Cologne, Gleueler Str. 24, D-50931, Cologne, Germany.
Frank ZauckeInstitute for Biochemistry II, Centre for Biochemistry, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, D-50931, Cologne, Germany.ORCID http://orcid.org/0000-0002-7680-9354
Markus PietschInstitute II for Pharmacology, Centre of Pharmacology, Medical Faculty, University of Cologne, Gleueler Str. 24, D-50931, Cologne, Germany. markus.pietsch@uk-koeln.de.
University of Cologne · DETH Köln - University of Applied Sciences · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The α

Indexed as

Calcium Channels, L-TypeEnzyme-Linked Immunosorbent AssayGabapentinHEK293 CellsHumansLigandsMass SpectrometryMembrane ProteinsThrombospondinsCalcium Channels, L-TypeGabapentinLigandsMembrane Proteinsthrombospondin 4Thrombospondins

Identifiers

PMID31700036
PMCPMC6838084
OpenAlexW2984900241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.