Evidence map›Paper›PMID 31699993›Full record

ReviewNature reviews. Disease primers2019

Craniopharyngioma.

Hermann L Müller, Thomas E Merchant, Monika Warmuth-Metz, Juan-Pedro Martinez-Barbera, Stephanie Puget

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Disease primers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 284 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
284citing papers in PubMed, 8 pooled it
28.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

284 citing papers in PubMed, 8 syntheses or guidelines pooled it, 507 citations in OpenAlex.

  1. Pooled it
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  20. Early Findings from the Multicenter RAPID Consortium on Papillary Craniopharyngiomas.Journal of neurological surgery. Part B, Skull base · 2026
    Article

224 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Hermann L MüllerDepartment of Pediatrics and Pediatric Hematology/Oncology, University Children's Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany. mueller.hermann@klinikum-oldenburg.de.
Thomas E MerchantDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Monika Warmuth-MetzDepartment of Neuroradiology, University Hospital, Würzburg, Germany.
Juan-Pedro Martinez-BarberaDevelopmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Stephanie PugetService de Neurochirurgie, Hôpital Necker-Enfants Malades, Sorbonne Paris Cité, Paris, France.
Klinikum Oldenburg · DESt. Jude Children's Research Hospital · USUniversitätsklinikum Würzburg · DEUniversité Paris Cité · FRUniversity College London · GB

Funding

Cancer Research UK 27727Medical Research Council MR/M000125/1
6 · The paper itself

Abstract

Craniopharyngiomas are rare malformational tumours of low histological malignancy arising along the craniopharyngeal duct. The two histological subtypes, adamantinomatous craniopharyngioma (ACP) and papillary craniopharyngioma (PCP), differ in genesis and age distribution. ACPs are diagnosed with a bimodal peak of incidence (5-15 years and 45-60 years), whereas PCPs are restricted to adults mainly in the fifth and sixth decades of life. ACPs are driven by somatic mutations in CTNNB1 (encoding β-catenin) that affect β-catenin stability and are predominantly cystic in appearance. PCPs frequently harbour somatic BRAF

Indexed as

Age FactorsCraniopharyngiomaHumansMagnetic Resonance ImagingNeurosurgical ProceduresObesityRadiotherapy

Identifiers

PMID31699993
OpenAlexW4211078220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.