Evidence map›Paper›PMID 31699787›Full record

ArticleHaematologica2020

Rare variants lowering the levels of coagulation factor X are protective against ischemic heart disease.

Elvezia Maria Paraboschi, Amit Vikram Khera, Piera Angelica Merlini, Laura Gigante, Flora Peyvandi, Mark Chaffin, Marzia Menegatti, Fabiana Busti, Domenico Girelli, Nicola Martinelli and 5 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Rare, Damaging DNA Variants inCirculation. Genomic and precision medicine · 2021
    Trial
  2. Article
  3. Review
  4. Gene-Environment Interactions for Cardiovascular Disease.Current atherosclerosis reports · 2021
    Review
  5. Article
  6. Aging · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Elvezia Maria ParaboschiDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
Amit Vikram KheraCenter for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Piera Angelica MerliniDivision of Cardiology, Azienda Ospedaliera Ospedale Niguarda Cà Granda, Milan, Italy.
Laura GiganteDivision of Cardiology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Flora PeyvandiAngelo Bianchi Bonomi Haemophilia and Thrombosis Centre, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Luigi Villa Foundation, Milan, Italy.
Mark ChaffinCenter for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Marzia MenegattiAngelo Bianchi Bonomi Haemophilia and Thrombosis Centre, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Luigi Villa Foundation, Milan, Italy.
Fabiana BustiDepartment of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy.
Domenico GirelliDepartment of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy.
Nicola MartinelliDepartment of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy.
Oliviero OlivieriDepartment of Medicine, Section of Internal Medicine, University of Verona, Verona, Italy.
Sekar KathiresanCenter for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Diego ArdissinoDivision of Cardiology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Rosanna AsseltaDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
Stefano DugaDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
University of Verona · ITHumanitas University · ITBroad Institute · USOspedale di Parma · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITMassachusetts General Hospital · USUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain IschemiaMyocardial IschemiaStrokeFactor XHumansFactor X

Identifiers

PMID31699787
PMCPMC7327651
OpenAlexW2986303437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.