Evidence map›Paper›PMID 31699634›Full record

ArticleSleep health2020

Obstructive sleep apnea risk and subclinical atherosclerosis in South Asians living in the United States.

Rupinder Deol, Kathryn A Lee, Alka M Kanaya, Namratha R Kandula

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sleep health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rupinder DeolDepartment of Family Health Care Nursing, University of California, San Francisco, San Francisco, CA 94143.
Kathryn A LeeDepartment of Family Health Care Nursing, University of California, San Francisco, San Francisco, CA 94143. Electronic address: Kathryn.lee@ucsf.edu.
Alka M KanayaEpidemiology & Biostatistics, School of Medicine, University of California, San Francisco, San Francisco, CA 94115.
Namratha R KandulaDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
University of California, San Francisco · USNorthwestern University · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
NURSING RESEARCH TRAINING IN SYMPTOM MANAGEMENTT32NR007088 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEE, KATHRYN · 1996 to 2015
$7.5M
Mediators of Atherosclerosis in South Asians Living in AmericaR01HL093009 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2010 to 2018
$5.4M
Ectopic fat and atherosclerosis in South AsiansK24HL112827 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2013 to 2022
$1.2M
NCATS NIH HHS UL1 TR000040NCRR NIH HHS UL1 RR024131NHLBI NIH HHS K24 HL112827NHLBI NIH HHS R01 HL093009NIDDK NIH HHS P30 DK092924NIDDK NIH HHS P30 DK098722NINR NIH HHS T32 NR007088
6 · The paper itself

Abstract

objectivesThe objective of this study was to examine the association between high risk of obstructive sleep apnea (OSA) and subclinical atherosclerosis among South Asians in the United States.

designA secondary analysis of cross-sectional data. SETTING/

participantsA community-based cohort of 906 men and women participating in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study. MEASUREMENTS: The Berlin Questionnaire was used to screen for OSA risk. Coronary artery calcium (CAC), common carotid artery intima-media thickness (IMT), and internal carotid artery IMT were used as measures of subclinical atherosclerosis.

resultsThe majority of participants (59%) with high OSA risk had CAC scores >0 compared with only 41% of participants with low OSA risk (P <.001). The high OSA risk group was older (P =.005), male (P =.04), had higher body mass index (P <.001) and had greater common carotid artery IMT (0.96 ± 0.27 mm) and internal carotid artery IMT (1.33 ± 0.42 mm) measurements. Snoring, sleep-disordered breathing (SDB), and high OSA risk were associated with subclinical atherosclerosis. However, only high OSA risk remained significant in multivariable models after controlling for demographic and clinical factors that included hypertension (HTN), obesity, diabetes, and dyslipidemia.

conclusionsHigh OSA risk, which includes overlapping comorbidities of HTN and obesity, was not associated with the time living in the US but was associated with subclinical atherosclerosis markers. These cardiovascular disease risk factors should include evaluation of the spectrum of SDB among all adults, including South Asian men and women.

Indexed as

Asymptomatic DiseasesAsianAtherosclerosisCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsSleep Apnea, ObstructiveUnited StatesCarotid intima-media thicknessCoronary artery calciumDaytime sleepinessHypertensionObesitySleep-disordered breathing

Identifiers

PMID31699634
PMCPMC6995439
OpenAlexW2982983604

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.