Evidence map›Paper›PMID 31699042›Full record

SynthesisBMC infectious diseases2019

Application of MALDI-TOF MS to rapid identification of anaerobic bacteria.

Ying Li, Mingzhu Shan, Zuobin Zhu, Xuhua Mao, Mingju Yan, Ying Chen, Qiuju Zhu, Hongchun Li, Bing Gu

Abstract readMeta-Analysis
In one paragraph

Synthesis in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Megaprosthesis Infection byClinical case reports · 2025
    Article
  7. Chronic osteoarthritis caused byJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Article
  8. Review
  9. Antibiotics (Basel, Switzerland) · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Is Propionimicrobium lymphophilum a new urinary tract infection cause?Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Differentiating betweenFoods (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ying LiSchool of Medical Technology, Xuzhou Medical University, Xuzhou, 221004, China.
Mingzhu ShanSchool of Medical Technology, Xuzhou Medical University, Xuzhou, 221004, China.
Zuobin ZhuDepartment of Genetics, Xuzhou Medical University, Xuzhou, 221004, China.
Xuhua MaoDepartment of Clinical Laboratory, Yixing People's Hospital, Wuxi, 214200, China.
Mingju YanSchool of Medical Technology, Xuzhou Medical University, Xuzhou, 221004, China.
Ying ChenSchool of Medical Technology, Xuzhou Medical University, Xuzhou, 221004, China.
Qiuju ZhuJiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, 221004, China.
Hongchun LiSchool of Medical Technology, Xuzhou Medical University, Xuzhou, 221004, China.
Bing GuSchool of Medical Technology, Xuzhou Medical University, Xuzhou, 221004, China. gb20031129@163.com.

Funding

Advanced health talent of six-one project of Jiangsu Province LGY2016042Jiangsu Privincial Medical Talent ZDRCA2016053Jiangsu Privincial Natural Science Foundation BK20151154Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province 17KJB360014Six talent peaks project of Jiangsu Province WSN-135the National Natural Science Foundation of China 81471994the National Natural Science Foundation of China 81871734the National Natural Science Foundation of China 81902040the Natural Science Foundation of Jiangsu Province Grants No BK20150209
6 · The paper itself

Abstract

backgroundMatrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been rapidly developed and widely used as an analytical technique in clinical laboratories with high accuracy in microorganism identification.

objectiveTo validate the efficacy of MALDI-TOF MS in identification of clinical pathogenic anaerobes.

methodsTwenty-eight studies covering 6685 strains of anaerobic bacteria were included in this meta-analysis. Fixed-effects models based on the P-value and the I-squared were used for meta-analysis to consider the possibility of heterogeneity between studies. Statistical analyses were performed by using STATA 12.0.

resultsThe identification accuracy of MALDI-TOF MS was 84% for species (I

conclusionsOur research showed that MALDI-TOF-MS was satisfactory in genus identification of clinical pathogenic anaerobic bacteria. However, this method still suffers from different drawbacks in precise identification of rare anaerobe and species levels of common anaerobic bacteria.

Indexed as

Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationBacteria, AnaerobicBacteroidesClostridiumLactobacillusPrevotellaAnaerobesBacteria identificationMALDI-TOF MS

Identifiers

PMID31699042
PMCPMC6836477

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.