ArticleHealthcare (Basel, Switzerland)2019
Comparison of Aggregated N-of-1 Trials with Parallel and Crossover Randomized Controlled Trials Using Simulation Studies.
Article in Healthcare (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review of N-of-1 Studies in Rare Genetic Neurodevelopmental Disorders: The Power of 1.Neurology · 2021Pooled it
- Comparison of Bayesian Networks, G-estimation and linear models to estimate causal treatment effects in aggregated N-of-1 trials with carry-over effects.BMC medical research methodology · 2023Trial
- Strengthening Rural Health With N-of-1 Trials and Single-Case Experimental Designs.The Australian journal of rural health · 2026Article
- N-of-1 trials in clinical research: Methodological foundations, statistical approaches and implementation challenges.British journal of clinical pharmacology · 2026Review
- From precision interventions to precision health.Nature communications · 2025Review
- Article
- A qualitative study on the facilitators and barriers to adopting the N-of-1 trial methodology as part of clinical practice: potential versus implementation challenges.International journal of qualitative studies on health and well-being · 2024Article
- The Potential of Integrative Cancer Treatment Using Melatonin and the Challenge of Heterogeneity in Population-Based Studies: A Case Report of Colon Cancer and a Literature Review.Current oncology (Toronto, Ont.) · 2024Review
- SECRETS: Subject-efficient clinical randomized controlled trials using synthetic intervention.Contemporary clinical trials communications · 2024Article
- Article
- Power analysis for idiographic (within-subject) clinical trials: Implications for treatments of rare conditions and precision medicine.Behavior research methods · 2023Article
- Problems With O'Connell et al, "Implanted Spinal Neuromodulation Interventions for Chronic Pain in Adults" (Cochrane Review).Neuromodulation : journal of the International Neuromodulation Society · 2023Article
- A Smartphone Intervention to Promote a Sustainable Healthy Diet: Protocol for a Pilot Study.JMIR research protocols · 2023Article
- Promoting Daily Well-being in Adolescents using mHealth.Journal of youth and adolescence · 2022Article
- Can we Reconcile Evidence-based Medicine with Personalized Medicine: Poised on a Cusp!Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- Multiple N-of-1 trials to investigate hypoxia therapy in Parkinson's disease: study rationale and protocol.BMC neurology · 2022Article
- StudyU: A Platform for Designing and Conducting Innovative Digital N-of-1 Trials.Journal of medical Internet research · 2022Article
- Article
- Genetically-Guided Medical Nutrition Therapy in Type 2 Diabetes Mellitus and Pre-diabetes: A Series ofFrontiers in nutrition · 2022Article
- Accommodating Serial Correlation and Sequential Design Elements in Personalized Studies and Aggregated Personalized Studies.Harvard data science review · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.