ArticleMedical sciences (Basel, Switzerland)2019
Lead Exposure and Cardiovascular Disease among Young and Middle-Aged Adults.
Article in Medical sciences (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Investigating the Interplay of Toxic Metals and Essential Elements in Cardiovascular Disease.Journal of xenobiotics · 2025Article
- Potential Health Risks of Lead Exposure from Early Life through Later Life: Implications for Public Health Education.International journal of environmental research and public health · 2022Article
- Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019.Frontiers in cardiovascular medicine · 2022Article
- Combined Effect of Lead Exposure and Allostatic Load on Cardiovascular Disease Mortality-A Preliminary Study.International journal of environmental research and public health · 2021Article
- Lead Distribution in Urban Soil in a Medium-Sized City: Household-Scale Analysis.Environmental science & technology · 2021Article
- Proximity to sources of airborne lead is associated with reductions in Children's executive function in the first four years of life.Health & place · 2021Article
- Article
- Cumulative Effects of Low-Level Lead Exposure and Chronic Physiological Stress on Hepatic Dysfunction-A Preliminary Study.Medical sciences (Basel, Switzerland) · 2020Article
- Effects of Vitamin D Receptor, Metallothionein 1A, and 2A Gene Polymorphisms on Toxicity of the Peripheral Nervous System in Chronically Lead-Exposed Workers.International journal of environmental research and public health · 2020Article
- Chronic Stress and Cardiovascular Disease among Individuals Exposed to Lead: A Pilot Study.Diseases (Basel, Switzerland) · 2020Article
- Human Health Risk Assessment for Toxic Trace Elements in the Yaro Mine and Reclamation Options.International journal of environmental research and public health · 2019Article
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1 author.
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Abstract
Lead and its effects on cardiovascular-related markers were explored in this cross-sectional study of young adults (18-44 years) and middle-aged adults (45-65 years) from the United States using the National Health and Nutrition Examination Survey (NHANES), 2009-2016. Degrees of exposure were created using blood lead level (BLL) as the biomarker of exposure based on the epidemiologically relevant threshold of BLL > 5 μg/dL. The mean values, in addition to the percentages of people represented for the markers of interest (systolic blood pressure [SBP], diastolic blood pressure [DBP], gamma-glutamyl transferase [GGT], non-high-density lipoprotein cholesterol [non-HDL-C]) were explored. Among those exposed to lead, the likelihood of elevated clinical markers (as defined by clinically relevant thresholds of above normal) were examined using binary logistic regression. In exploring exposure at the 5 μg/dL levels, there were significant differences in all the mean variables of interest between young and middle-aged adults. The binary logistic regression showed young and middle-aged adults exposed to lead were significantly more likely to have elevated markers (apart from DBP). In all, lead affects cardiovascular-related markers in young and middle-aged U.S. adults and thus we must continue to monitor lead exposure to promote health.
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