Evidence map›Paper›PMID 31698413›Full record

ArticleNature2020

Structure of the human metapneumovirus polymerase phosphoprotein complex.

Junhua Pan, Xinlei Qian, Simon Lattmann, Abbas El Sahili, Tiong Han Yeo, Huan Jia, Tessa Cressey, Barbara Ludeke, Sarah Noton, Marian Kalocsay and 2 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 133 citations in OpenAlex.

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  19. Structural insights into the dynamic mechanism of bornavirus polymerase.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Junhua Pan *Division of Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. pan@crystal.harvard.edu.
Xinlei Qian *School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Simon LattmannNTU Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore.
Abbas El SahiliSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Tiong Han YeoSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Huan JiaSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Tessa CresseyBoston University School of Medicine, National Emerging Infectious Diseases Laboratories, Boston, MA, USA.
Barbara LudekeBoston University School of Medicine, National Emerging Infectious Diseases Laboratories, Boston, MA, USA.
Sarah NotonBoston University School of Medicine, National Emerging Infectious Diseases Laboratories, Boston, MA, USA.
Marian KalocsayLaboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
Rachel FearnsBoston University School of Medicine, National Emerging Infectious Diseases Laboratories, Boston, MA, USA. rfearns@bu.edu.
Julien LescarSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore. julien@ntu.edu.sg.
Boston University · USNanyang Technological University · SGSingapore-MIT Alliance for Research and Technology · SGBoston Children's Hospital · USHarvard University · US

Funding

Virology CoreP01AI089618 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI Jiwon Lee · 2011 to 2026
$40.0M
BIOLOGY OF THE LUNG--MULTIDISCIPLINARY PROGRAMT32HL007035 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Darrell N. Kotton, JOSEPH P MIZGERD · 1985 to 2026
$24.3M
Initiation and regulation of RSV mRNA transcription and genome replicationR01AI113321 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FEARNS, RACHEL · 2014 to 2017
$1.7M
NHLBI NIH HHS T32 HL007035NIAID NIH HHS P01 AI089618NIAID NIH HHS R01 AI113321
6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) cause severe respiratory diseases in infants and elderly adults

Indexed as

Amino Acid SequenceAnimalsCell LineCryoelectron MicroscopyMetapneumovirusModels, MolecularPhosphoproteinsProtein BindingProtein Structure, QuaternaryRNA-Dependent RNA PolymerasePhosphoproteinsRNA-Dependent RNA Polymerase

Identifiers

PMID31698413
PMCPMC6949429
OpenAlexW2985832396

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.