Evidence map›Paper›PMID 31698139›Full record

SynthesisPublic health2020

Prevalence of hypercholesterolemia in Nigeria: a systematic review and meta-analysis.

D Adeloye, D Q Abaa, E O Owolabi, B M Ale, R G Mpazanje, M T Dewan, C Omoyele, N Ezeigwe, W Alemu, M O Harhay and 2 more

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  8. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
  9. Prediction of hypercholesterolemia using machine learning techniques.Journal of diabetes and metabolic disorders · 2023
    Article
  10. Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 6 countries.

D AdeloyeCentre for Global Health, Usher Institute, University of Edinburgh, UK; RcDavies Evidence-based Medicine, Lagos, Nigeria. Electronic address: Davies.Adeloye@ed.ac.uk.
D Q AbaaSolina Centre for International Development and Research (SCIDaR), Abuja, Nigeria.
E O OwolabiDepartment of Nursing Sciences, University of Fort Hare, East London, South Africa.
B M AleINSERM UMR 1219, Bordeaux Population Health Research Center, Bordeaux, France; Holo Healthcare Limited, Nairobi, Kenya.
R G MpazanjeWHO Nigeria Country Office, Abuja, Nigeria.
M T DewanWHO Nigeria Country Office, Abuja, Nigeria.
C OmoyeleFederal Ministry of Health, Abuja, Nigeria.
N EzeigweFederal Ministry of Health, Abuja, Nigeria.
W AlemuInternational Health Consultancy, LLC, Atlanta, Georgia, USA.
M O HarhayDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine University of Pennsylvania Philadelphia, Pennsylvania, USA; Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
A AutaSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Fylde Road, Preston, UK.
I F AdewoleCollege of Medicine, University of Ibadan, Ibadan, Nigeria.
Federal Ministry of Health · NGWorld Health Organization - Nigeria · NGCentre for Global Health Research · CAInserm · FRSolina Group (Nigeria) · NGUniversity of Fort Hare · ZAUniversity of Ibadan · NGUniversity of Lancashire · GBUniversity of Pennsylvania · US

Funding

Improving the measurement and analysis of long-term, patient-centered outcomes following acute respiratory failureR00HL141678 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HARHAY, MICHAEL OSCAR · 2020 to 2022
$747k
Improving the measurement and analysis of long-term, patient-centered outcomes following acute respiratory failureK99HL141678 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HARHAY, MICHAEL OSCAR · 2018 to 2019
$214k
NHLBI NIH HHS K99 HL141678NHLBI NIH HHS R00 HL141678World Health Organization 001
6 · The paper itself

Abstract

objectivesElevated blood cholesterol (hypercholesterolemia) is a significant cause of cardiovascular disease. We aimed to estimate national and zonal prevalence of hypercholesterolemia in Nigeria to help guide targeted public health programs. STUDY

designThis is a systematic review and synthesis of publicly available epidemiologic data on hypercholesterolemia in Nigeria.

methodsWe systematically searched MEDLINE, EMBASE, Global Health, and Africa Journals Online for studies on the prevalence of hypercholesterolemia in Nigeria published between 1990 and 2018. We used a random-effects meta-analysis (Freeman-Tukey double arcsine transformation) and meta-regression model to estimate the prevalence of hypercholesterolemia in Nigeria in 1995 and 2015.

resultsIn total, 13 studies (n = 16,981) were retrieved. The pooled crude prevalence of hypercholesterolemia in Nigeria was 38% (95% confidence interval: 26-51), with prevalence in women slightly higher (42%, 23-63) compared with men (38%, 20-58). The prevalence was highest in the South-south (53%, 38-68) and lowest in the South-west (3%, 2-4) and North-east (4%, 2-7). Urban dwellers had a significantly higher rate (52%, 24-79) compared with rural dwellers (10%, 6-15). We estimated over 8.2 million persons (age-adjusted prevalence 16.5%) aged 20 years or more had hypercholesterolemia in Nigeria in 1995, increasing to 21.9 million persons (age-adjusted prevalence 25.9%) in 2015.

conclusionsOur findings suggest a high prevalence of hypercholesterolemia in Nigeria. Urbanization, lifestyles, diets, and culture appear to be driving an increasing prevalence, especially among women. Population-wide awareness and education on reducing elevated cholesterol levels and associated risks should be prioritized.

Indexed as

HumansHypercholesterolemiaNigeriaPrevalenceRisk FactorsDyslipidemiaHypercholesterolemiaIschemic heart diseaseNigeriaPrevalence

Identifiers

PMID31698139
PMCPMC6994374
OpenAlexW2988030222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.