Evidence map›Paper›PMID 31698075›Full record

ArticleJournal of structural biology2020

Conformational properties of l-fucose and the tetrasaccharide building block of the sulfated l-fucan from Lytechinus variegatus.

Francisco F Bezerra, William P Vignovich, AyoOluwa O Aderibigbe, Hao Liu, Joshua S Sharp, Robert J Doerksen, Vitor H Pomin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of structural biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Sulfated polysaccharide fromFood chemistry: X · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Francisco F BezerraInstitute of Medical Biochemistry Leopoldo de Meis, University Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro 21941, RJ, Brazil.
William P VignovichBioMolecular Sciences Department, School of Pharmacy, University of Mississippi, University, 38677 MS, USA.
AyoOluwa O AderibigbeBioMolecular Sciences Department, School of Pharmacy, University of Mississippi, University, 38677 MS, USA.
Hao LiuBioMolecular Sciences Department, School of Pharmacy, University of Mississippi, University, 38677 MS, USA.
Joshua S SharpBioMolecular Sciences Department, School of Pharmacy, University of Mississippi, University, 38677 MS, USA; Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, 38677 MS, USA.
Robert J DoerksenBioMolecular Sciences Department, School of Pharmacy, University of Mississippi, University, 38677 MS, USA; Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, 38677 MS, USA.
Vitor H PominInstitute of Medical Biochemistry Leopoldo de Meis, University Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro 21941, RJ, Brazil; BioMolecular Sciences Department, School of Pharmacy, University of Mississippi, University, 38677 MS, USA; Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, 38677 MS, USA. Electronic address: vpomin@olemiss.edu.
University of Mississippi · USUniversidade Federal do Rio de Janeiro · BR

Funding

TR&D3. Approaches to Proteoglycan Function at Biochemical and Cellular LevelsP41GM103390 · NIGMS · UNIVERSITY OF GEORGIA · PI MOREMEN, KELLEY W. · 2012 to 2019
$14.5M
RENOVATION OF FOURTH FLOOR OF FASER HALLC06RR014503 · NCRR · UNIVERSITY OF MISSISSIPPI · PI WELLS, BARBARA G · 1999 to 1999
–
NCRR NIH HHS C06 RR014503NIGMS NIH HHS P41 GM103390
6 · The paper itself

Abstract

Although the 3D structure of carbohydrates is known to contribute to their biological roles, conformational studies of sugars are challenging because their chains are flexible in solution and consequently the number of 3D structural restraints is limited. Here, we investigate the conformational properties of the tetrasaccharide building block of the Lytechinus variegatus sulfated fucan composed of the following structure [l-Fucp4(SO

Indexed as

Molecular ConformationAnimalsCarbohydratesFucoseLytechinusMagnetic Resonance SpectroscopyMolecular Dynamics SimulationOligosaccharidesPolysaccharidesCarbohydratesFucoseOligosaccharidesPolysaccharidesConformationFucoseNMR spectroscopyStructural glycobiologySulfated fucan

Identifiers

PMID31698075
PMCPMC7810140
OpenAlexW2985416789

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.