Evidence map›Paper›PMID 31697874›Full record

ArticleMolecules and cells2019

Overexpression and Selective Anticancer Efficacy of

Choa Park, Yejin Lee, Soyeon Je, Shengzhi Chang, Nayoung Kim, Euna Jeong, Sukjoon Yoon

Open access · greenAbstract read
In one paragraph

Article in Molecules and cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 34 citations in OpenAlex.

  1. The moonlighting functions of glycolytic enzymes in tumorigenesis.Cellular oncology (Dordrecht, Netherlands) · 2026
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  8. BeyondMolecular therapy oncolytics · 2023
    Review
  9. Article
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  15. Article
  16. ENO3 promotes colorectal cancer progression by enhancing cell glycolysis.Medical oncology (Northwood, London, England) · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Choa ParkDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Yejin LeeDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Soyeon JeDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Shengzhi ChangDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Nayoung KimDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Euna JeongResearch Institute of Women's Health, Sookmyung Women's University, Seoul 04310, Korea.
Sukjoon YoonDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Sookmyung Women's University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncogenic gain-of-function mutations are clinical biomarkers for most targeted therapies, as well as represent direct targets for drug treatment. Although loss-of-function mutations involving the tumor suppressor gene,

Indexed as

Gain of Function MutationGene Expression Regulation, NeoplasticA549 CellsAdenocarcinomaAMP-Activated Protein Kinase KinasesBiomarkers, TumorCell Line, TumorCell ProliferationCell SurvivalGene Expression ProfilingHumansLung NeoplasmsPhosphopyruvate HydrataseProtein Serine-Threonine KinasesRNA InterferenceAMP-Activated Protein Kinase KinasesBiomarkers, TumorPhosphopyruvate HydrataseProtein Serine-Threonine KinasesSTK11 protein, humanEnolase 3lung adenocarcinomaSTK11 loss-offunction mutation

Identifiers

PMID31697874
PMCPMC6883975
OpenAlexW3009767836

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.