Evidence map›Paper›PMID 31697854›Full record

ArticleJournal of mass spectrometry : JMS2020

High-resolution ion mobility spectrometry-mass spectrometry of isomeric/isobaric ribonucleotide variants.

Thomas Kenderdine, Reza Nemati, Andrew Baker, Martin Palmer, Jakub Ujma, Molly FitzGibbon, Limin Deng, Maksim Royzen, James Langridge, Daniele Fabris

Abstract read
In one paragraph

Article in Journal of mass spectrometry : JMS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Analysis of RNA and Its Modifications.Annual review of analytical chemistry (Palo Alto, Calif.) · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Enhancing the Depth of Analyses with Next-Generation Ion Mobility Experiments.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Epitranscriptomics of SARS-CoV-2 Infection.Frontiers in cell and developmental biology · 2022
    Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thomas KenderdineDepartments of Chemistry and Biological Sciences, University at Albany, Albany, New York, 12222, USA.
Reza NematiBioassay and High Throughput Screening Department, Biogen, Cambridge, Massachusetts, 02142, USA.
Andrew BakerResearch and Development, Waters Corporation, Wilmslow, SK9 4AX, UK.
Martin PalmerResearch and Development, Waters Corporation, Wilmslow, SK9 4AX, UK.
Jakub UjmaResearch and Development, Waters Corporation, Wilmslow, SK9 4AX, UK.ORCID https://orcid.org/0000-0002-2751-7750
Molly FitzGibbonDepartments of Chemistry and Biological Sciences, University at Albany, Albany, New York, 12222, USA.
Limin DengDepartments of Chemistry and Biological Sciences, University at Albany, Albany, New York, 12222, USA.
Maksim RoyzenDepartments of Chemistry and Biological Sciences, University at Albany, Albany, New York, 12222, USA.
James LangridgeResearch and Development, Waters Corporation, Wilmslow, SK9 4AX, UK.
Daniele FabrisDepartments of Chemistry and Biological Sciences, University at Albany, Albany, New York, 12222, USA.ORCID https://orcid.org/0000-0003-0786-1578

Funding

Modulation of RNA modifications by RNA virusesR01GM123050 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI FABRIS, DANIELE, PAGER, CARA THERESIA · 2018 to 2021
$1.9M
Characterization of ncRNAs' post-transcriptional modifications by antisense affinity capture and MS analysisR01GM121844 · NIGMS · UNIVERSITY OF CONNECTICUT STORRS · PI FABRIS, DANIELE · 2017 to 2021
$1.6M
Role of Post-transcription RNA Modifications on Zika Virus Gene ExpressionR21AI133617 · NIAID · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI FABRIS, DANIELE, PAGER, CARA THERESIA · 2017 to 2018
$486k
NIAID NIH HHS R21 AI133617NIGMS NIH HHS R01 GM121844NIGMS NIH HHS R01 GM123050NIH HHS R01 GM121844-01NIH HHS R21 AI133617-01
6 · The paper itself

Abstract

In this report, we explored the benefits of cyclic ion mobility (cIM) mass spectrometry in the analysis of isomeric post-transcriptional modifications of RNA. Standard methyl-cytidine samples were initially utilized to test the ability to correctly distinguish different structures sharing the same elemental composition and thus molecular mass. Analyzed individually, the analytes displayed characteristic arrival times (t

Indexed as

HeLa CellsHumansIon Mobility SpectrometryIsomerismMass SpectrometryRibonucleotidesRibonucleotides

Identifiers

PMID31697854
PMCPMC8363168

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.