Evidence map›Paper›PMID 31697426›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2020

Bridging and Conformational Control of Porphyrin Units through Non-Traditional Rigid Scaffolds.

Nitika Grover, Gemma M Locke, Keith J Flanagan, Michael H R Beh, Alison Thompson, Mathias O Senge

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Bicyclo[1.1.1]pentane Ketones via Friedel-Crafts Acylation.The Journal of organic chemistry · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nitika GroverSchool of Chemistry, SFI Tetrapyrrole Laboratory, Trinity College Dublin, Trinity Biomedical Sciences Institute, The University of Dublin, 152-160 Pearse Street, Dublin, 2, Ireland.
Gemma M LockeSchool of Chemistry, SFI Tetrapyrrole Laboratory, Trinity College Dublin, Trinity Biomedical Sciences Institute, The University of Dublin, 152-160 Pearse Street, Dublin, 2, Ireland.
Keith J FlanaganSchool of Chemistry, SFI Tetrapyrrole Laboratory, Trinity College Dublin, Trinity Biomedical Sciences Institute, The University of Dublin, 152-160 Pearse Street, Dublin, 2, Ireland.
Michael H R BehSchool of Chemistry, SFI Tetrapyrrole Laboratory, Trinity College Dublin, Trinity Biomedical Sciences Institute, The University of Dublin, 152-160 Pearse Street, Dublin, 2, Ireland.
Alison ThompsonDepartment of Chemistry, Dalhousie University, P.O. Box 15000, Halifax, Nova Scotia, B3H 4R2, Canada.
Mathias O SengeSchool of Chemistry, SFI Tetrapyrrole Laboratory, Trinity College Dublin, Trinity Biomedical Sciences Institute, The University of Dublin, 152-160 Pearse Street, Dublin, 2, Ireland.ORCID http://orcid.org/0000-0002-7467-1654

Funding

Ireland-Canada University Foundation Dobbin Atlantic ScholarshipIrish Research Council GOIPG/2015/3700Science Foundation Ireland IvP 13/IA/1894Technische Universität München August-Wilhelm Scheer Gastprofessor
6 · The paper itself

Abstract

Connecting two porphyrin units in a rigid linear fashion, without any undesired electron delocalization or communication between the chromophores, remains a synthetic challenge. Herein, a broad library of functionally diverse multi-porphyrin arrays that incorporate the non-traditional rigid linker groups cubane and bicyclo[1.1.1]pentane (BCP) is described. A robust, reliable, and versatile synthetic procedure was employed to access porphyrin-cubane/BCP-porphyrin arrays, representing the largest non-polymeric structures available for cubane/BCP derivatives. These reactions demonstrate considerable substrate scope, from utilization of small phenyl moieties to large porphyrin rings, with varying lengths and different angles. To control conformational flexibility, amide bonds were introduced between the bridgehead carbon of BCP/cubane and the porphyrin rings. Through varying the orientation of the substituents around the amide bond of cubane/BCP, different intermolecular interactions were identified through single crystal X-ray analysis. These studies revealed non-covalent interactions that are the first-of-their-kind including a unique iodine-oxygen interaction between cubane units. These supramolecular architectures indicate the possibility to mimic a protein structure due to the sp

Indexed as

bicyclo[1.1.1]pentanecubanemolecular tweezersporphyrin arrayssupramolecular chemistry

Identifiers

PMID31697426
PMCPMC7064986

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.