Evidence map›Paper›PMID 31697371›Full record

Trial reportPain medicine (Malden, Mass.)2021

Mobile Neurofeedback for Pain Management in Veterans with TBI and PTSD.

Eric B Elbogen, Amber Alsobrooks, Sara Battles, Kiera Molloy, Paul A Dennis, Jean C Beckham, Samuel A McLean, Julian R Keith, Carmen Russoniello

Registry-linked trialOpen access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Pain medicine (Malden, Mass.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02237885 (Pain Management Using Mobile Technology in Veterans With PTSD and TBI), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02237885 nacompletednot on this map

Pain Management Using Mobile Technology in Veterans With PTSD and TBI

TypeinterventionalSponsorDuke UniversityRan2015 to 2017Enrolled41ConditionsChronic Pain, Posttraumatic Stress Disorders, Traumatic Brain InjuryArmsNeuroSky MindWave Mobile
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Review
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  13. Advances in Pain Medicine: a Review of New Technologies.Current pain and headache reports · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Eric B ElbogenVeterans Affairs (VA) Mid-Atlantic Mental Illness Research, Education and Clinical Center (MIRECC), Durham, North Carolina, USA.
Amber AlsobrooksDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Sara BattlesDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Kiera MolloyDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Paul A DennisVeterans Affairs (VA) Mid-Atlantic Mental Illness Research, Education and Clinical Center (MIRECC), Durham, North Carolina, USA.
Jean C BeckhamVeterans Affairs (VA) Mid-Atlantic Mental Illness Research, Education and Clinical Center (MIRECC), Durham, North Carolina, USA.
Samuel A McLeanDepartment of Anesthesiology, University of North Carolina-Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
Julian R KeithDepartment of Psychology, University of North Carolina-Wilmington, Wilmington, North Carolina, USA.
Carmen RussonielloCenter for Applied Psychophysiology, East Carolina University, Greenville, North Carolina, USA.
Duke University · USEast Carolina University · USUniversity of North Carolina at Chapel Hill · USUniversity of North Carolina Wilmington · US

Funding

Pain Management using Mobile Technology in Veterans with PTSD and TBIR34AT008399 · NCCIH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELBOGEN, ERIC B. · 2014 to 2016
$677k
NCCIH NIH HHS R34 AT008399
6 · The paper itself

Abstract

objectiveChronic pain is common in military veterans with traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD). Neurofeedback, or electroencephalograph (EEG) biofeedback, has been associated with lower pain but requires frequent travel to a clinic. The current study examined feasibility and explored effectiveness of neurofeedback delivered with a portable EEG headset linked to an application on a mobile device.

designOpen-label, single-arm clinical trial.

settingHome, outside of clinic. SUBJECTS: N = 41 veterans with chronic pain, TBI, and PTSD.

methodVeterans were instructed to perform "mobile neurofeedback" on their own for three months. Clinical research staff conducted two home visits and two phone calls to provide technical assistance and troubleshoot difficulties.

resultsN = 36 veterans returned for follow-up at three months (88% retention). During this time, subjects completed a mean of 33.09 neurofeedback sessions (10 minutes each). Analyses revealed that veterans reported lower pain intensity, pain interference, depression, PTSD symptoms, anger, sleep disturbance, and suicidal ideation after the three-month intervention compared with baseline. Comparing pain ratings before and after individual neurofeedback sessions, veterans reported reduced pain intensity 67% of the time immediately following mobile neurofeedback. There were no serious adverse events reported.

conclusionsThis preliminary study found that veterans with chronic pain, TBI, and PTSD were able to use neurofeedback with mobile devices independently after modest training and support. While a double-blind randomized controlled trial is needed for confirmation, the results show promise of a portable, technology-based neuromodulatory approach for pain management with minimal side effects.

Indexed as

Brain Injuries, TraumaticNeurofeedbackStress Disorders, Post-TraumaticVeteransHumansPain ManagementChronic PainMilitary VeteransNeurofeedbackPost-traumatic Stress DisorderTraumatic Brain Injury

Identifiers

PMID31697371
PMCPMC7901853
OpenAlexW2983365778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.