Evidence map›Paper›PMID 31697108›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2020

Depression, perceived social control, and hypothalamic-pituitary-adrenal axis function in African-American adults.

Ezemenari M Obasi, Tzu-An Chen, Lucia Cavanagh, B Katherine Smith, Kristin A Wilborn, Lorna H McNeill, Lorraine R Reitzel

Abstract read
In one paragraph

Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ezemenari M ObasiDepartment of Psychological, Health, & Learning Sciences.
Tzu-An ChenHEALTH Research Institute.
Lucia CavanaghDepartment of Psychological, Health, & Learning Sciences.
B Katherine SmithDepartment of Psychological, Health, & Learning Sciences.
Kristin A WilbornDepartment of Psychological, Health, & Learning Sciences.
Lorna H McNeillDepartment of Health Disparities Research.
Lorraine R ReitzelDepartment of Psychological, Health, & Learning Sciences.

Funding

Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
Testing a Digital Therapeutic for Smoking Cessation among Hispanic Persons who SmokeU54MD015946 · NIMHD · UNIVERSITY OF HOUSTON · PI Bettina M. Beech · 2020 to 2026
$22.0M
Stress and Drug Use Vulnerability in the African American CommunityR01DA034739 · NIDA · UNIVERSITY OF HOUSTON · PI OBASI, EZEMENARI M · 2013 to 2017
$2.5M
The Impact of COVID-19 Pandemic on Cancer Care and Health-Related Quality of Life of Racial and Ethnic Minority Women Diagnosed with Breast CancerP20CA221697 · NCI · UNIVERSITY OF HOUSTON · PI REITZEL, LORRAINE R · 2017 to 2020
$1.7M
Pilot Project 1: Mexican immigrants' biological and behavioral cancer risk based on stressP20CA221696 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MCNEILL, LORNA H. · 2017 to 2020
$1.1M
NCATS NIH HHS UL1 TR003167NCI NIH HHS P20 CA221696NCI NIH HHS P20 CA221697NIDA NIH HHS R01 DA034739NIH HHSNIMHD NIH HHS U54 MD015946
6 · The paper itself

Abstract

objectiveSocial determinants may negatively affect health via Hypothalamic-Pituitary-Adrenal (HPA) axis dysfunction. The potential contribution of social determinants and related factors to HPA-axis functioning is important to study among African American adults, who are more likely to experience societal inequities and health disparities relative to other racial/ethnic groups. This study examined the relationship between depressive symptoms and perceived social control on HPA-axis functioning among African American adults.

methodParticipants (N = 107; Mage = 50, 79% female) were administered measures including the Center for Epidemiologic Studies-Depression and Informal (neighborhood) Social Control. Study procedures included the provision of 6 saliva samples for cortisol analysis (at wakeup, 30- and 90-min post-wakeup, 2:00 PM, 5:00 PM, and prebedtime). The relationship between depression and social control on the functioning of the HPA-axis were simultaneously examined within a 2-level hierarchical linear model.

resultsVariability in the Cortisol Awakening Response (CAR) was accounted for by depressive symptomatology (p = .023) and perceived social control (p = .016), whereby greater depression was associated with a blunted CAR (less awakening cortisol production) and greater perceptions of neighborhood social control with a higher CAR.

conclusionsElevated depressive symptoms and low perceptions of neighborhood social control may serve as mechanisms that help to explain within-group variability in the functioning of stress physiology among African American adults. Findings enhance understanding of how social determinants may affect African Americans' health. (PsycINFO Database Record (c) 2020 APA, all rights reserved).

Indexed as

AdultAgedBlack or African AmericanDepressionFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemMaleMiddle AgedSalivaSocial Control, FormalYoung AdultHydrocortisone

Identifiers

PMID31697108
PMCPMC6957753

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.