ArticleThe Australian and New Zealand journal of psychiatry2020
Cortical thinning in dementia with Lewy bodies and Parkinson disease dementia.
Article in The Australian and New Zealand journal of psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 22 citations in OpenAlex.
- Gray Matter Microstructure Measured Using Diffusion Imaging as a Biomarker of Severity in Lewy Body Diseases.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Selective molecular and network architecture features underlie brain cortical atrophy in dementia with Lewy bodies.Journal of biomedical science · 2026Article
- Amyloid and Tau Co-pathology in Parkinson Disease and Atypical Parkinsonism.Current neurology and neuroscience reports · 2026Review
- Quantitative susceptibility mapping reveals differences between subtypes of Lewy body dementia.Brain : a journal of neurology · 2026Article
- Evidence for divergent cortical organisation in Parkinson's disease and Lewy Body Dementia.Nature communications · 2025Article
- High-magnitude headers are not associated with structural and functional brain changes in active high-level football (soccer) players.BMJ open sport & exercise medicine · 2025Article
- Assessment of cerebral perfusion alterations in dementia with Lewy bodies and Alzheimer's disease.Quantitative imaging in medicine and surgery · 2024Article
- Automated brain segmentation and volumetry in dementia diagnostics: a narrative review with emphasis on FreeSurfer.Frontiers in aging neuroscience · 2024Review
- Changes of brain structure and structural covariance networks in Parkinson's disease associated cognitive impairment.Frontiers in aging neuroscience · 2024Article
- Article
- Cerebral cortical thickness and cognitive decline in Parkinson's disease.Cerebral cortex communications · 2023Article
- Structural brain changes in patients with persistent headache after COVID-19 resolution.Journal of neurology · 2023Article
- A Preliminary Comparison of the Methylome and Transcriptome from the Prefrontal Cortex Across Alzheimer's Disease and Lewy Body Dementia.Journal of Alzheimer's disease reports · 2023Article
- Differentiating dementia with Lewy bodies from Alzheimer's disease and Parkinson's disease dementia: an update on imaging modalities.Journal of neurology · 2022Review
- Comparing the Clinical and Neuropsychological Characteristics of Parkinson's Disease With and Without Freezing of Gait.Frontiers in neuroscience · 2021Article
- Morphological Changes in Cortical and Subcortical Structures in Multiple System Atrophy Patients With Mild Cognitive Impairment.Frontiers in human neuroscience · 2021Article
- Cortical circuit dysfunction in a mouse model of alpha-synucleinopathyBrain communications · 2021Article
- Sex differences for regional pathology in people with a high likelihood of Lewy body dementia phenotype based on underlying pathology.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundWe investigated the structural changes associated with Alzheimer's disease, dementia with Lewy bodies and Parkinson disease dementia by means of cortical thickness analysis.
methodsTwo hundred and forty-five participants: 76 Alzheimer's disease, 65 dementia with Lewy bodies, 29 Parkinson disease dementia and 76 cognitively normal controls underwent 3-T T1-weighted magnetic resonance imaging and clinical and cognitive assessments. We implemented FreeSurfer to obtain cortical thickness estimates to contrast patterns of cortical thinning across groups and their clinical correlates.
resultsIn Alzheimer's disease and dementia with Lewy bodies, a largely similar pattern of regional cortical thinning was observed relative to controls apart from a more severe loss within the entorhinal and parahippocampal structures in Alzheimer's disease. In Parkinson disease dementia, regional cortical thickness was indistinguishable from controls and dementia with Lewy bodies, suggesting an 'intermediate' pattern of regional cortical change. In terms of global cortical thickness, group profiles were controls > Parkinson disease dementia > dementia with Lewy bodies > Alzheimer's disease (F
conclusionIn a large and well-characterised cohort of people with dementia, regional cortical thinning in dementia with Lewy bodies was broadly similar to Alzheimer's disease. There was preservation of the medial temporal lobe structures in dementia with Lewy bodies compared with Alzheimer's disease, supporting its inclusion as a supportive biomarker in the revised clinical criteria for dementia with Lewy bodies. However, there was less global cortical thinning in Parkinson disease dementia, with no significant regional difference between Parkinson disease dementia and controls. These findings highlight the overlap across the Alzheimer's disease/Parkinson disease dementia spectrum and the potential for differing mechanisms underlying neurodegeneration and cognition in dementia with Lewy bodies and Parkinson disease dementia.
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